Conformational analysis of Ac-NPGQ-NH2 and Ac-VPaH-NH 2 by vibrational circular dichroism spectroscopy combined with molecular dynamics and quantum chemical calculations

Attila Borics, Richard F. Murphy, Sándor Lovas

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Conformational properties of two potentially β-turn forming peptides were determined using a strategy which combines MD simulations, IR and VCD spectroscopy and quantum chemical calculations. This strategy could be a useful alternative for solution conformational analysis of short flexible peptides and could help to identify VCD features which are as yet unknown.

Original languageEnglish
Pages (from-to)353-359
Number of pages7
JournalProtein and Peptide Letters
Volume14
Issue number4
DOIs
StatePublished - Apr 2007

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Circular dichroism spectroscopy
Vibrational spectroscopy
Molecular Dynamics Simulation
Circular Dichroism
Molecular dynamics
Spectrum Analysis
Peptides
Spectroscopy
acetyl-asparagyl-prolyl-glycyl-glutaminamide

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology

Cite this

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