Content of commercially available, single-ingredient vitamin D dietary supplements

Laura A.G. Armas, Philip Gregory, Ronald L. Horst

Research output: Contribution to journalArticlepeer-review


With the increased Institute of Medicine recommendation for vitamin D, more consumers are taking vitamin D from over-the-counter or prescription sources. The purpose of this study was to determine the content of commercially available, single-ingredient vitamin D supplements. Eleven commercially available dietary supplement calciferol products were purchased, repackaged, and analyzed for vitamin D content in a laboratory that was blinded to brand or manufacturer of the supplement. Vitamin D was extracted and isolated for analysis by a high-performance liquid chromatography method. Measured vitamin D content was compared with the stated label amount of vitamin D. The percentage of actual vitamin D contained in the supplements ranged from 82% and 119% of the stated label amount. Despite anecdotal reports of products with substantial content deviations from the labeled amount, no remarkable departures from labeled content were found in this set of vitamin D preparations.

Original languageEnglish (US)
Pages (from-to)54-56
Number of pages3
JournalJournal of Evidence-Based Complementary and Alternative Medicine
Issue number1
StatePublished - Jan 2012

All Science Journal Classification (ASJC) codes

  • Complementary and alternative medicine


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