Abstract
This paper describes case reports and pharmacokinetic information regarding the continuous intravenous administration of naloxone in treatment of narcotic overdose. Continuous naloxone infusion has been used successfully in acutely narcotized patients, and a review of the pharmacodynamic and pharmacokinetic properties of naloxone indicate the reasons for this mode of administration. Summaries of clinical studies in support of the infusion method are given. A naloxone protocol is outlined.
| Original language | English |
|---|---|
| Pages (from-to) | 945-950 |
| Number of pages | 6 |
| Journal | Annals of Pharmacotherapy |
| Volume | 15 |
| Issue number | 12 |
| DOIs | |
| State | Published - 1981 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Pharmacology (medical)
Cite this
Continuous infusion of naloxone in the treatment of narcotic overdose. / Bradberry, J. Chris; Raebel, Marsha A.
In: Annals of Pharmacotherapy, Vol. 15, No. 12, 1981, p. 945-950.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Continuous infusion of naloxone in the treatment of narcotic overdose
AU - Bradberry, J. Chris
AU - Raebel, Marsha A.
PY - 1981
Y1 - 1981
N2 - This paper describes case reports and pharmacokinetic information regarding the continuous intravenous administration of naloxone in treatment of narcotic overdose. Continuous naloxone infusion has been used successfully in acutely narcotized patients, and a review of the pharmacodynamic and pharmacokinetic properties of naloxone indicate the reasons for this mode of administration. Summaries of clinical studies in support of the infusion method are given. A naloxone protocol is outlined.
AB - This paper describes case reports and pharmacokinetic information regarding the continuous intravenous administration of naloxone in treatment of narcotic overdose. Continuous naloxone infusion has been used successfully in acutely narcotized patients, and a review of the pharmacodynamic and pharmacokinetic properties of naloxone indicate the reasons for this mode of administration. Summaries of clinical studies in support of the infusion method are given. A naloxone protocol is outlined.
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UR - http://www.scopus.com/inward/citedby.url?scp=84970540428&partnerID=8YFLogxK
U2 - 10.1177/106002808101501205
DO - 10.1177/106002808101501205
M3 - Article
C2 - 7338189
AN - SCOPUS:84970540428
VL - 15
SP - 945
EP - 950
JO - Annals of Pharmacotherapy
JF - Annals of Pharmacotherapy
SN - 1060-0280
IS - 12
ER -