Contraction and relaxation of rabbit basilar artery by thiopental

C. E. Gross, Peter W. Abel

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Tension measurements were made on rabbit basilar artery segments to test the direct effect of thiopental on serotonin (5HT)- and norepinephrine (NE)-induced contraction. At concentrations of 3 x 10-5M or greater, thiopental caused relaxation of NE-induced tension. Thiopental doses greater than 3 x 10-4M had a similar relaxing effect on 5HT-induced contraction. However, thiopental doses below 3 x 10-4M demonstrated an unexpected dose-dependent potentiation of the 5HT-induced contraction.

Original languageEnglish
Pages (from-to)433-435
Number of pages3
JournalNeurosurgery
Volume17
Issue number3
StatePublished - 1985
Externally publishedYes

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Basilar Artery
Thiopental
Rabbits
Norepinephrine
Serotonin

All Science Journal Classification (ASJC) codes

  • Clinical Neurology
  • Surgery

Cite this

Contraction and relaxation of rabbit basilar artery by thiopental. / Gross, C. E.; Abel, Peter W.

In: Neurosurgery, Vol. 17, No. 3, 1985, p. 433-435.

Research output: Contribution to journalArticle

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