Coronary Artery Disease Prognosis and C-Reactive Protein Levels Improve in Proportion to Percent Lowering of Low-Density Lipoprotein

James H. O'Keefe, Loren Cordain, Philip G. Jones, Hussam Abuissa

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

This editorial outlines the data supporting aggressive lipid goals and options for treating low-density lipoprotein (LDL) cholesterol to a range of approximately 30 to 70 mg/dl. The physiologically normal cholesterol range is approximately 30 to 70 mg/dl for native hunter-gatherers, healthy human neonates, free-living primates, and virtually all wild mammals. Randomized statin trials in patients with recent acute coronary syndromes and stable coronary artery disease have demonstrated that cardiovascular events are reduced and cardiovascular survival optimized when LDL cholesterol is reduced to

Original languageEnglish
Pages (from-to)135-139
Number of pages5
JournalAmerican Journal of Cardiology
Volume98
Issue number1
DOIs
StatePublished - Jul 1 2006
Externally publishedYes

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LDL Lipoproteins
C-Reactive Protein
LDL Cholesterol
Coronary Artery Disease
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Acute Coronary Syndrome
Primates
Mammals
Reference Values
Cholesterol
Newborn Infant
Lipids
Survival

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Coronary Artery Disease Prognosis and C-Reactive Protein Levels Improve in Proportion to Percent Lowering of Low-Density Lipoprotein. / O'Keefe, James H.; Cordain, Loren; Jones, Philip G.; Abuissa, Hussam.

In: American Journal of Cardiology, Vol. 98, No. 1, 01.07.2006, p. 135-139.

Research output: Contribution to journalArticle

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