Coronary Artery Disease Prognosis and C-Reactive Protein Levels Improve in Proportion to Percent Lowering of Low-Density Lipoprotein

James H. O'Keefe; Loren Cordain; Philip G. Jones; Hussam Abuissa

doi:10.1016/j.amjcard.2006.01.062

Coronary Artery Disease Prognosis and C-Reactive Protein Levels Improve in Proportion to Percent Lowering of Low-Density Lipoprotein

James H. O'Keefe, Loren Cordain, Philip G. Jones, Hussam Abuissa

Research output: Contribution to journal › Comment/debate

14 Scopus citations

Abstract

This editorial outlines the data supporting aggressive lipid goals and options for treating low-density lipoprotein (LDL) cholesterol to a range of approximately 30 to 70 mg/dl. The physiologically normal cholesterol range is approximately 30 to 70 mg/dl for native hunter-gatherers, healthy human neonates, free-living primates, and virtually all wild mammals. Randomized statin trials in patients with recent acute coronary syndromes and stable coronary artery disease have demonstrated that cardiovascular events are reduced and cardiovascular survival optimized when LDL cholesterol is reduced to

Original language	English (US)
Pages (from-to)	135-139
Number of pages	5
Journal	American Journal of Cardiology
Volume	98
Issue number	1
DOIs	https://doi.org/10.1016/j.amjcard.2006.01.062
State	Published - Jul 1 2006
Externally published	Yes

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All Science Journal Classification (ASJC) codes

Cardiology and Cardiovascular Medicine

Cite this

O'Keefe, J. H., Cordain, L., Jones, P. G., & Abuissa, H. (2006). Coronary Artery Disease Prognosis and C-Reactive Protein Levels Improve in Proportion to Percent Lowering of Low-Density Lipoprotein. American Journal of Cardiology, 98(1), 135-139. https://doi.org/10.1016/j.amjcard.2006.01.062

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Access to Document

10.1016/j.amjcard.2006.01.062