Corynebacterium infections

Stephen J. Cavalieri, Floyd C. Knoop

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The corynebacteria are gram-positive bacilli that are nonspore forming club-shaped rods. The name is derived from the Greek koryne, which stands for club. In a typical Gram stain these bacteria appear as V-in Y-shaped arrangements or in clumps that resemble Chinese letters. Corynebacteria are nonmotile, catalase positive, aerobic, and contain metachromatic granules when stained with methylene blue. They are ubiquitous and can be found on the skin and in the upper respiratory and gastrointestinal tracts. The primary pathogen in this group is Corynebacterium diphtheriae, the etiologic agent of diphtheria. Additional corynebacteria include 45 species, 30 of which on rare occasion cause human disease. The nondiphtheria corynebacteria are increasingly recognized as agents of human disease in immunocompromised patients, and may also, although infrequently, infect healthy adults. Included in this group are C. ulcerans, C. minutissimum, C. pseudodiphtheriticum, C. striatum, C. urealyticum, C. riegelii, and C. glucuronolyticum are uncommon and include respiratory tract infections, ....

Original languageEnglish (US)
Title of host publicationxPharm
Subtitle of host publicationThe Comprehensive Pharmacology Reference
PublisherElsevier Inc.
Pages1-5
Number of pages5
ISBN (Print)9780080552323
DOIs
Publication statusPublished - Dec 1 2011

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All Science Journal Classification (ASJC) codes

  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Cavalieri, S. J., & Knoop, F. C. (2011). Corynebacterium infections. In xPharm: The Comprehensive Pharmacology Reference (pp. 1-5). Elsevier Inc.. https://doi.org/10.1016/B978-008055232-3.60858-X