Abstract
The effect of Ca2+ on the glucose transporter of human erythrocytes was investigated. The results showed that Ca2+ had no effect. But, the glucose transport of extracellular Ca2+ erythrocytes was markedly inhibited due to the increase in Ca2+ concentration by addition of ionophore A23187. The Ca2+ inhibition exhibited a dose-dependent manner with apparent half maximal concentration of 250 μM and could not be recovered by 10 mM EGTA. Unlike Ca2+ glucose transporter Mg2+ did not affect the glucose transporter.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 383-391 |
| Number of pages | 9 |
| Journal | Biochemistry and Molecular Biology International |
| Volume | 36 |
| Issue number | 2 |
| State | Published - Dec 1 1995 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Biochemistry
- Molecular Biology
- Genetics
Cite this
Tu, Y. P., Xiao, L., Su, X. F., & Yang, F. Y. (1995). Cytoplasmic Ca2+ inhibits the glucose transporter of human erythrocytes. Biochemistry and Molecular Biology International, 36(2), 383-391.