Darbepoetin alfa administered every three weeks is effective for the treatment of chemotherapy-induced anemia

Ralph Boccia; Imtiaz A. Malik; Vinay Raja; Stephen Kahanic; Randall Liu; Tom Lillie; Dianne Tomita; Billy Clowney; Peter Silberstein

doi:10.1634/theoncologist.11-4-409

Darbepoetin alfa administered every three weeks is effective for the treatment of chemotherapy-induced anemia

Ralph Boccia, Imtiaz A. Malik, Vinay Raja, Stephen Kahanic, Randall Liu, Tom Lillie, Dianne Tomita, Billy Clowney, Peter Silberstein

Department of Medicine

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

Patients with cancer receiving chemotherapy often have chemotherapy-induced anemia (CIA) and reduced quality of life. Darbepoetin alfa can effectively treat CIA when administered at an extended dosing interval of once every 3 weeks (Q3W). Darbepoetin alfa administered Q3W may allow synchronization of darbepoetin alfa therapy with chemotherapy administered Q3W. This multicenter, open-label, 16-week study evaluated the effectiveness and safety of darbepoetin alfa administered as a fixed dose (300 μg) Q3W in patients with CIA. Eligible patients (≥18 years) were anemic (hemoglobin

Original language	English (US)
Pages (from-to)	409-417
Number of pages	9
Journal	Oncologist
Volume	11
Issue number	4
DOIs	https://doi.org/10.1634/theoncologist.11-4-409
State	Published - Apr 2006

All Science Journal Classification (ASJC) codes

Oncology
Cancer Research

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abstract = "Patients with cancer receiving chemotherapy often have chemotherapy-induced anemia (CIA) and reduced quality of life. Darbepoetin alfa can effectively treat CIA when administered at an extended dosing interval of once every 3 weeks (Q3W). Darbepoetin alfa administered Q3W may allow synchronization of darbepoetin alfa therapy with chemotherapy administered Q3W. This multicenter, open-label, 16-week study evaluated the effectiveness and safety of darbepoetin alfa administered as a fixed dose (300 μg) Q3W in patients with CIA. Eligible patients (≥18 years) were anemic (hemoglobin ",

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AU - Boccia, Ralph

AU - Malik, Imtiaz A.

AU - Raja, Vinay

AU - Kahanic, Stephen

AU - Liu, Randall

AU - Lillie, Tom

AU - Tomita, Dianne

AU - Clowney, Billy

AU - Silberstein, Peter

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AB - Patients with cancer receiving chemotherapy often have chemotherapy-induced anemia (CIA) and reduced quality of life. Darbepoetin alfa can effectively treat CIA when administered at an extended dosing interval of once every 3 weeks (Q3W). Darbepoetin alfa administered Q3W may allow synchronization of darbepoetin alfa therapy with chemotherapy administered Q3W. This multicenter, open-label, 16-week study evaluated the effectiveness and safety of darbepoetin alfa administered as a fixed dose (300 μg) Q3W in patients with CIA. Eligible patients (≥18 years) were anemic (hemoglobin

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Darbepoetin alfa administered every three weeks is effective for the treatment of chemotherapy-induced anemia

Abstract

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