Dehydration of threonine esters during tosylation

C. Somlai, Sándor Lovas, P. Forgó, R. F. Murphy, B. Penke

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Abstract

Tosylation of N-α-protected threonine methyl-and benzyl esters was investigated. Depending on the protecting groups, the composition of the reaction mixtures showed different ratio between O-tosyl-and dehydrothreonine derivatives. The latter was formed exclusively in case of N-α-Fmoc-threonine benzyl ester.

Original languageEnglish
Pages (from-to)3633-3640
Number of pages8
JournalSynthetic Communications
Volume31
Issue number23
DOIs
Publication statusPublished - 2001
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Organic Chemistry

Cite this

Somlai, C., Lovas, S., Forgó, P., Murphy, R. F., & Penke, B. (2001). Dehydration of threonine esters during tosylation. Synthetic Communications, 31(23), 3633-3640. https://doi.org/10.1081/SCC-100107012