Dermal toxicity and microscopic alterations by JP-8 jet fuel components in vivo in rabbit

Somnath Singh, Jagdish Singh

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

In this study, we investigated the skin irritation, macroscopic and microscopic barrier alteration in vivo in rabbits from aliphatic and aromatic components of jet propellant-8 (JP-8) jet fuel. Macroscopic barrier properties were evaluated by measuring transepidermal water loss (TEWL), skin capacitance, and skin temperature; microscopic changes were observed by light microscopy. Draize visual scoring system was used to measure skin irritation. We found significant (P

Original languageEnglish (US)
Pages (from-to)153-161
Number of pages9
JournalEnvironmental Toxicology and Pharmacology
Volume16
Issue number3
DOIs
StatePublished - Apr 1 2004

All Science Journal Classification (ASJC) codes

  • Toxicology
  • Pharmacology
  • Health, Toxicology and Mutagenesis

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