TY - JOUR
T1 - Dermal toxicity and microscopic alterations by JP-8 jet fuel components in vivo in rabbit
AU - Singh, Somnath
AU - Singh, Jagdish
N1 - Funding Information:
We acknowledge the financial support from the US Department of Defense, Air Force Office of Scientific Research Grant # F 49620-99-1-0223. We also thank Sumeet Rastogi for his help during in vivo irritation experiments.
PY - 2004/4
Y1 - 2004/4
N2 - In this study, we investigated the skin irritation, macroscopic and microscopic barrier alteration in vivo in rabbits from aliphatic and aromatic components of jet propellant-8 (JP-8) jet fuel. Macroscopic barrier properties were evaluated by measuring transepidermal water loss (TEWL), skin capacitance, and skin temperature; microscopic changes were observed by light microscopy. Draize visual scoring system was used to measure skin irritation. We found significant (P
AB - In this study, we investigated the skin irritation, macroscopic and microscopic barrier alteration in vivo in rabbits from aliphatic and aromatic components of jet propellant-8 (JP-8) jet fuel. Macroscopic barrier properties were evaluated by measuring transepidermal water loss (TEWL), skin capacitance, and skin temperature; microscopic changes were observed by light microscopy. Draize visual scoring system was used to measure skin irritation. We found significant (P
UR - http://www.scopus.com/inward/record.url?scp=1542404535&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=1542404535&partnerID=8YFLogxK
U2 - 10.1016/j.etap.2003.12.001
DO - 10.1016/j.etap.2003.12.001
M3 - Article
C2 - 21782702
AN - SCOPUS:1542404535
VL - 16
SP - 153
EP - 161
JO - Environmental Toxicology and Pharmacology
JF - Environmental Toxicology and Pharmacology
SN - 1382-6689
IS - 3
ER -