Dermal toxicity and microscopic alterations by JP-8 jet fuel components in vivo in rabbit

Somnath Singh; Jagdish Singh

doi:10.1016/j.etap.2003.12.001

Dermal toxicity and microscopic alterations by JP-8 jet fuel components in vivo in rabbit

Somnath Singh, Jagdish Singh

Department of Pharmacy Sciences

Research output: Contribution to journal › Article

2 Scopus citations

Abstract

In this study, we investigated the skin irritation, macroscopic and microscopic barrier alteration in vivo in rabbits from aliphatic and aromatic components of jet propellant-8 (JP-8) jet fuel. Macroscopic barrier properties were evaluated by measuring transepidermal water loss (TEWL), skin capacitance, and skin temperature; microscopic changes were observed by light microscopy. Draize visual scoring system was used to measure skin irritation. We found significant (P

Original language	English (US)
Pages (from-to)	153-161
Number of pages	9
Journal	Environmental Toxicology and Pharmacology
Volume	16
Issue number	3
DOIs	https://doi.org/10.1016/j.etap.2003.12.001
State	Published - Apr 1 2004

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All Science Journal Classification (ASJC) codes

Toxicology
Pharmacology
Health, Toxicology and Mutagenesis

Cite this

Singh, S., & Singh, J. (2004). Dermal toxicity and microscopic alterations by JP-8 jet fuel components in vivo in rabbit. Environmental Toxicology and Pharmacology, 16(3), 153-161. https://doi.org/10.1016/j.etap.2003.12.001

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Access to Document

10.1016/j.etap.2003.12.001