Design and testing of a white-light, steady-state diffuse reflectance spectrometer for determination of optical properties of highly scattering systems

Michael G. Nichols; Edward L. Hull; Thomas H. Foster

doi:10.1364/AO.36.000093

Design and testing of a white-light, steady-state diffuse reflectance spectrometer for determination of optical properties of highly scattering systems

Michael G. Nichols, Edward L. Hull, Thomas H. Foster

Department of Physics

Research output: Contribution to journal › Article

165 Scopus citations

Abstract

We present a steady-state radially resolved diffuse reflectance spectrometer capable of measuring the absorption and transport scattering spectra of tissue-simulating phantoms over an adjustable 170-nm wavelength interval in the visible and near infrared. Measurements in a variety of phantoms are demonstrated over the relevant range of tissue optical properties, and the accuracy of the instrument is found to be approximately 10% in both scattering and absorption. Monte Carlo simulations designed to test the accuracy of the instrument are presented that support the experimental findings.

Original language	English (US)
Pages (from-to)	93-104
Number of pages	12
Journal	Applied Optics
Volume	36
Issue number	1
DOIs	https://doi.org/10.1364/AO.36.000093
State	Published - Jan 1 1997

Fingerprint

All Science Journal Classification (ASJC) codes

Atomic and Molecular Physics, and Optics
Engineering (miscellaneous)
Electrical and Electronic Engineering

Cite this

Nichols, M. G., Hull, E. L., & Foster, T. H. (1997). Design and testing of a white-light, steady-state diffuse reflectance spectrometer for determination of optical properties of highly scattering systems. Applied Optics, 36(1), 93-104. https://doi.org/10.1364/AO.36.000093

@article{f6eb5971b0e44e95b9c689dda9a995d0,

title = "Design and testing of a white-light, steady-state diffuse reflectance spectrometer for determination of optical properties of highly scattering systems",

abstract = "We present a steady-state radially resolved diffuse reflectance spectrometer capable of measuring the absorption and transport scattering spectra of tissue-simulating phantoms over an adjustable 170-nm wavelength interval in the visible and near infrared. Measurements in a variety of phantoms are demonstrated over the relevant range of tissue optical properties, and the accuracy of the instrument is found to be approximately 10% in both scattering and absorption. Monte Carlo simulations designed to test the accuracy of the instrument are presented that support the experimental findings.",

author = "Nichols, {Michael G.} and Hull, {Edward L.} and Foster, {Thomas H.}",

year = "1997",

month = jan

day = "1",

doi = "10.1364/AO.36.000093",

language = "English (US)",

volume = "36",

pages = "93--104",

journal = "Applied Optics",

issn = "1559-128X",

publisher = "The Optical Society",

number = "1",

}

TY - JOUR

T1 - Design and testing of a white-light, steady-state diffuse reflectance spectrometer for determination of optical properties of highly scattering systems

AU - Nichols, Michael G.

AU - Hull, Edward L.

AU - Foster, Thomas H.

PY - 1997/1/1

Y1 - 1997/1/1

N2 - We present a steady-state radially resolved diffuse reflectance spectrometer capable of measuring the absorption and transport scattering spectra of tissue-simulating phantoms over an adjustable 170-nm wavelength interval in the visible and near infrared. Measurements in a variety of phantoms are demonstrated over the relevant range of tissue optical properties, and the accuracy of the instrument is found to be approximately 10% in both scattering and absorption. Monte Carlo simulations designed to test the accuracy of the instrument are presented that support the experimental findings.

AB - We present a steady-state radially resolved diffuse reflectance spectrometer capable of measuring the absorption and transport scattering spectra of tissue-simulating phantoms over an adjustable 170-nm wavelength interval in the visible and near infrared. Measurements in a variety of phantoms are demonstrated over the relevant range of tissue optical properties, and the accuracy of the instrument is found to be approximately 10% in both scattering and absorption. Monte Carlo simulations designed to test the accuracy of the instrument are presented that support the experimental findings.

UR - http://www.scopus.com/inward/record.url?scp=0030855571&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030855571&partnerID=8YFLogxK

U2 - 10.1364/AO.36.000093

DO - 10.1364/AO.36.000093

M3 - Article

C2 - 18250650

AN - SCOPUS:0030855571

VL - 36

SP - 93

EP - 104

JO - Applied Optics

JF - Applied Optics

SN - 1559-128X

IS - 1

ER -

Access to Document

10.1364/AO.36.000093