Determination of blood flow in the finger using near-infrared spectroscopy

Marc Rendell, Chad Hovelson, Kelly O'Connor, Lance Cheung, Scott Huard, Tae Sok Kong, Anthony Catania, Robert Rosenthal

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Wavelengths in the near-infrared range have much better penetrance in organic substances than visible light. We used near-infrared spectroscopy to determine non-invasively blood flow in the fingertip. We used laser Doppler technology to measure skin blood flow as a comparison procedure. We performed several manoeuvres to change blood flow. These included restriction of flow, thermal stimulation and post-occlusion hyperaemia. Near-infrared measurements had coefficients of variation of 10-15% at the various wavelengths, contrasting with variability of 30-40% with laser Doppler measurement. With restriction of blood flow, there was a downward shift in the absorbance curve. With thermal stimulation and with post-occlusion hyperaemia, there was a rise in the curve. The flow-induced shifts in the absorbance curve were particularly pronounced in the range of 850-970 nm. The correlation between absorbance values and laser Doppler-determined blood flow was also highest in this range, averaging about 0.69 (n = 625). Near-infrared spectroscopy can therefore be used to scan the fingertip. The absorbances obtained do reflect changes in blood flow. There is a correlation with skin blood flow, although near-infrared measurements are affected by blood flow in the full breadth of the finger, not just the skin. We can measure this blood flow with significant reproducibility. It may be possible to use near-infrared spectroscopy to measure the concentration of individual blood components.

Original languageEnglish (US)
Pages (from-to)426-434
Number of pages9
JournalClinical Physiology
Issue number5
StatePublished - 1998

All Science Journal Classification (ASJC) codes

  • Physiology


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