Dietary supplements for osteoarthritis

Philip J. Gregory, Morgan Sperry, Amy Friedman Wilson

Research output: Contribution to journalReview article

69 Citations (Scopus)

Abstract

A large number of dietary supplements are promoted to patients with osteoarthritis and as many as one third of those patients have used a supplement to treat their condition. Glucosamine-containing supplements are among the most commonly used products for osteoarthritis. Although the evidence is not entirely consistent, most research suggests that glucosamine sulfate can improve symptoms of pain related to osteoarthritis, as well as slow disease progression in patients with osteoarthritis of the knee. Chondroitin sulfate also appears to reduce osteoarthritis symptoms and is often combined with glucosamine, but there is no reliable evidence that the combination is more effective than either agent alone. S-adenosylmethionine may reduce pain but high costs and product quality issues limit its use. Several other supplements are promoted for treating osteoarthritis, such as methylsulfonylmethane, Harpagophytum procumbens (devil's claw), Curcuma longa (turmeric), and Zingiber officinale (ginger), but there is insufficient reliable evidence regarding long-term safety or effectiveness.

Original languageEnglish
Pages (from-to)177-184
Number of pages8
JournalAmerican Family Physician
Volume77
Issue number2
StatePublished - Jan 15 2008

Fingerprint

Dietary Supplements
Osteoarthritis
Harpagophytum
Glucosamine
Ginger
Curcuma
Pain
S-Adenosylmethionine
Chondroitin Sulfates
Knee Osteoarthritis
Disease Progression
Safety
Costs and Cost Analysis
Research

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Gregory, P. J., Sperry, M., & Wilson, A. F. (2008). Dietary supplements for osteoarthritis. American Family Physician, 77(2), 177-184.

Dietary supplements for osteoarthritis. / Gregory, Philip J.; Sperry, Morgan; Wilson, Amy Friedman.

In: American Family Physician, Vol. 77, No. 2, 15.01.2008, p. 177-184.

Research output: Contribution to journalReview article

Gregory, PJ, Sperry, M & Wilson, AF 2008, 'Dietary supplements for osteoarthritis', American Family Physician, vol. 77, no. 2, pp. 177-184.
Gregory PJ, Sperry M, Wilson AF. Dietary supplements for osteoarthritis. American Family Physician. 2008 Jan 15;77(2):177-184.
Gregory, Philip J. ; Sperry, Morgan ; Wilson, Amy Friedman. / Dietary supplements for osteoarthritis. In: American Family Physician. 2008 ; Vol. 77, No. 2. pp. 177-184.
@article{7461c476c2484c83b70ce2ba47fe5c70,
title = "Dietary supplements for osteoarthritis",
abstract = "A large number of dietary supplements are promoted to patients with osteoarthritis and as many as one third of those patients have used a supplement to treat their condition. Glucosamine-containing supplements are among the most commonly used products for osteoarthritis. Although the evidence is not entirely consistent, most research suggests that glucosamine sulfate can improve symptoms of pain related to osteoarthritis, as well as slow disease progression in patients with osteoarthritis of the knee. Chondroitin sulfate also appears to reduce osteoarthritis symptoms and is often combined with glucosamine, but there is no reliable evidence that the combination is more effective than either agent alone. S-adenosylmethionine may reduce pain but high costs and product quality issues limit its use. Several other supplements are promoted for treating osteoarthritis, such as methylsulfonylmethane, Harpagophytum procumbens (devil's claw), Curcuma longa (turmeric), and Zingiber officinale (ginger), but there is insufficient reliable evidence regarding long-term safety or effectiveness.",
author = "Gregory, {Philip J.} and Morgan Sperry and Wilson, {Amy Friedman}",
year = "2008",
month = "1",
day = "15",
language = "English",
volume = "77",
pages = "177--184",
journal = "American Family Physician",
issn = "0002-838X",
publisher = "American Academy of Family Physicians",
number = "2",

}

TY - JOUR

T1 - Dietary supplements for osteoarthritis

AU - Gregory, Philip J.

AU - Sperry, Morgan

AU - Wilson, Amy Friedman

PY - 2008/1/15

Y1 - 2008/1/15

N2 - A large number of dietary supplements are promoted to patients with osteoarthritis and as many as one third of those patients have used a supplement to treat their condition. Glucosamine-containing supplements are among the most commonly used products for osteoarthritis. Although the evidence is not entirely consistent, most research suggests that glucosamine sulfate can improve symptoms of pain related to osteoarthritis, as well as slow disease progression in patients with osteoarthritis of the knee. Chondroitin sulfate also appears to reduce osteoarthritis symptoms and is often combined with glucosamine, but there is no reliable evidence that the combination is more effective than either agent alone. S-adenosylmethionine may reduce pain but high costs and product quality issues limit its use. Several other supplements are promoted for treating osteoarthritis, such as methylsulfonylmethane, Harpagophytum procumbens (devil's claw), Curcuma longa (turmeric), and Zingiber officinale (ginger), but there is insufficient reliable evidence regarding long-term safety or effectiveness.

AB - A large number of dietary supplements are promoted to patients with osteoarthritis and as many as one third of those patients have used a supplement to treat their condition. Glucosamine-containing supplements are among the most commonly used products for osteoarthritis. Although the evidence is not entirely consistent, most research suggests that glucosamine sulfate can improve symptoms of pain related to osteoarthritis, as well as slow disease progression in patients with osteoarthritis of the knee. Chondroitin sulfate also appears to reduce osteoarthritis symptoms and is often combined with glucosamine, but there is no reliable evidence that the combination is more effective than either agent alone. S-adenosylmethionine may reduce pain but high costs and product quality issues limit its use. Several other supplements are promoted for treating osteoarthritis, such as methylsulfonylmethane, Harpagophytum procumbens (devil's claw), Curcuma longa (turmeric), and Zingiber officinale (ginger), but there is insufficient reliable evidence regarding long-term safety or effectiveness.

UR - http://www.scopus.com/inward/record.url?scp=38549167939&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=38549167939&partnerID=8YFLogxK

M3 - Review article

VL - 77

SP - 177

EP - 184

JO - American Family Physician

JF - American Family Physician

SN - 0002-838X

IS - 2

ER -