Direct oral anticoagulants for the prevention of stroke in nonvalvular atrial fibrillation

Eric B. Hoie, Karen K. O’Brien, Katie Neighbors, Shana L. Castillo, Kimberley J. Begley

Research output: Contribution to specialist publicationArticle

Abstract

Atrial fibrillation (AF) is the most common cardiac arrhythmia in the United States. It is a complicated disease state involving an irregular heart rate and rhythm. AF generally affects the aging population and is classified as either valvular AF (VAF) or nonvalvular AF (NVAF). The two differ based on the patient’s valve status and treatment strategies. AF treatment is directed toward rate control, with or without rhythm control, and anticoagulation for prevention of cardioembolic stroke. Several direct oral anticoagulants (edoxaban, apixaban, rivaroxaban, dabigatran) have recently gained approval for use in NVAF. Pharmacists should educate patients about potential drug-drug interactions and adverse effects with this class of medications.

Original languageEnglish (US)
Pages32-35
Number of pages4
Volume42
No2
Specialist publicationU.S. Pharmacist
StatePublished - Feb 2017

All Science Journal Classification (ASJC) codes

  • Pharmacy
  • Pharmacology
  • Pharmaceutical Science

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  • Cite this

    Hoie, E. B., O’Brien, K. K., Neighbors, K., Castillo, S. L., & Begley, K. J. (2017). Direct oral anticoagulants for the prevention of stroke in nonvalvular atrial fibrillation. U.S. Pharmacist, 42(2), 32-35.