Distinct genotypic clusters of heterogeneously and homogeneously methicillin-resistant Staphylococcus aureus from a Greek hospital

P. T. Tassios, A. C. Vatopoulos, A. Xanthaki, E. Mainas, Richard V. Goering, N. J. Legakis

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) strains isolated over a one-year period from a Greek hospital were tested for their levels of resistance to methicillin by population analysis. Heterogeneously resistant strains belonged to classes I, II, and II/III, whereas homogeneously resistant ones belonged to class IV. Strains of all classes possessed the mecA gene. Pulsed-field gel electrophoresis (PFGE) of Smal-digested genomic DNA revealed that all heterogeneously resistant strains were related. Homogeneously resistant strains were also closely related, but in a cluster distinct from the heterogeneous one. The methicillin-sensitive strains displayed a greater variety of PFGE types compared to MRSA isolates.

Original languageEnglish
Pages (from-to)170-173
Number of pages4
JournalEuropean Journal of Clinical Microbiology and Infectious Diseases
Volume16
Issue number2
DOIs
StatePublished - 1997

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Pulsed Field Gel Electrophoresis
Methicillin-Resistant Staphylococcus aureus
Methicillin Resistance
Methicillin
DNA
Population
Genes

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Immunology

Cite this

Distinct genotypic clusters of heterogeneously and homogeneously methicillin-resistant Staphylococcus aureus from a Greek hospital. / Tassios, P. T.; Vatopoulos, A. C.; Xanthaki, A.; Mainas, E.; Goering, Richard V.; Legakis, N. J.

In: European Journal of Clinical Microbiology and Infectious Diseases, Vol. 16, No. 2, 1997, p. 170-173.

Research output: Contribution to journalArticle

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