Distinct genotypic clusters of heterogeneously and homogeneously methicillin-resistant Staphylococcus aureus from a Greek hospital

P. T. Tassios; A. C. Vatopoulos; A. Xanthaki; E. Mainas; R. V. Goering; N. J. Legakis

doi:10.1007/BF01709481

Distinct genotypic clusters of heterogeneously and homogeneously methicillin-resistant Staphylococcus aureus from a Greek hospital

P. T. Tassios, A. C. Vatopoulos, A. Xanthaki, E. Mainas, R. V. Goering, N. J. Legakis

Department of Medical Microbiology and Immunology

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) strains isolated over a one-year period from a Greek hospital were tested for their levels of resistance to methicillin by population analysis. Heterogeneously resistant strains belonged to classes I, II, and II/III, whereas homogeneously resistant ones belonged to class IV. Strains of all classes possessed the mecA gene. Pulsed-field gel electrophoresis (PFGE) of Smal-digested genomic DNA revealed that all heterogeneously resistant strains were related. Homogeneously resistant strains were also closely related, but in a cluster distinct from the heterogeneous one. The methicillin-sensitive strains displayed a greater variety of PFGE types compared to MRSA isolates.

Original language	English (US)
Pages (from-to)	170-173
Number of pages	4
Journal	European Journal of Clinical Microbiology and Infectious Diseases
Volume	16
Issue number	2
DOIs	https://doi.org/10.1007/BF01709481
State	Published - Apr 8 1997

All Science Journal Classification (ASJC) codes

Microbiology (medical)
Infectious Diseases

Access to Document

10.1007/BF01709481

Cite this

Distinct genotypic clusters of heterogeneously and homogeneously methicillin-resistant Staphylococcus aureus from a Greek hospital. / Tassios, P. T.; Vatopoulos, A. C.; Xanthaki, A.; Mainas, E.; Goering, R. V.; Legakis, N. J.

In: European Journal of Clinical Microbiology and Infectious Diseases, Vol. 16, No. 2, 08.04.1997, p. 170-173.

Research output: Contribution to journal › Article › peer-review

@article{5e62561d51e448148b362c63f6b4ff39,

title = "Distinct genotypic clusters of heterogeneously and homogeneously methicillin-resistant Staphylococcus aureus from a Greek hospital",

abstract = "Methicillin-resistant Staphylococcus aureus (MRSA) strains isolated over a one-year period from a Greek hospital were tested for their levels of resistance to methicillin by population analysis. Heterogeneously resistant strains belonged to classes I, II, and II/III, whereas homogeneously resistant ones belonged to class IV. Strains of all classes possessed the mecA gene. Pulsed-field gel electrophoresis (PFGE) of Smal-digested genomic DNA revealed that all heterogeneously resistant strains were related. Homogeneously resistant strains were also closely related, but in a cluster distinct from the heterogeneous one. The methicillin-sensitive strains displayed a greater variety of PFGE types compared to MRSA isolates.",

author = "Tassios, {P. T.} and Vatopoulos, {A. C.} and A. Xanthaki and E. Mainas and Goering, {R. V.} and Legakis, {N. J.}",

year = "1997",

month = apr,

day = "8",

doi = "10.1007/BF01709481",

language = "English (US)",

volume = "16",

pages = "170--173",

journal = "European Journal of Clinical Microbiology and Infectious Diseases",

issn = "0934-9723",

publisher = "Springer Verlag",

number = "2",

}

TY - JOUR

T1 - Distinct genotypic clusters of heterogeneously and homogeneously methicillin-resistant Staphylococcus aureus from a Greek hospital

AU - Tassios, P. T.

AU - Vatopoulos, A. C.

AU - Xanthaki, A.

AU - Mainas, E.

AU - Goering, R. V.

AU - Legakis, N. J.

PY - 1997/4/8

Y1 - 1997/4/8

N2 - Methicillin-resistant Staphylococcus aureus (MRSA) strains isolated over a one-year period from a Greek hospital were tested for their levels of resistance to methicillin by population analysis. Heterogeneously resistant strains belonged to classes I, II, and II/III, whereas homogeneously resistant ones belonged to class IV. Strains of all classes possessed the mecA gene. Pulsed-field gel electrophoresis (PFGE) of Smal-digested genomic DNA revealed that all heterogeneously resistant strains were related. Homogeneously resistant strains were also closely related, but in a cluster distinct from the heterogeneous one. The methicillin-sensitive strains displayed a greater variety of PFGE types compared to MRSA isolates.

AB - Methicillin-resistant Staphylococcus aureus (MRSA) strains isolated over a one-year period from a Greek hospital were tested for their levels of resistance to methicillin by population analysis. Heterogeneously resistant strains belonged to classes I, II, and II/III, whereas homogeneously resistant ones belonged to class IV. Strains of all classes possessed the mecA gene. Pulsed-field gel electrophoresis (PFGE) of Smal-digested genomic DNA revealed that all heterogeneously resistant strains were related. Homogeneously resistant strains were also closely related, but in a cluster distinct from the heterogeneous one. The methicillin-sensitive strains displayed a greater variety of PFGE types compared to MRSA isolates.

UR - http://www.scopus.com/inward/record.url?scp=0030981388&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030981388&partnerID=8YFLogxK

U2 - 10.1007/BF01709481

DO - 10.1007/BF01709481

M3 - Article

C2 - 9105849

AN - SCOPUS:0030981388

VL - 16

SP - 170

EP - 173

JO - European Journal of Clinical Microbiology and Infectious Diseases

JF - European Journal of Clinical Microbiology and Infectious Diseases

SN - 0934-9723

IS - 2

ER -

Distinct genotypic clusters of heterogeneously and homogeneously methicillin-resistant Staphylococcus aureus from a Greek hospital

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this