Distinct genotypic clusters of heterogeneously and homogeneously methicillin-resistant Staphylococcus aureus from a Greek hospital

P. T. Tassios, A. C. Vatopoulos, A. Xanthaki, E. Mainas, Richard V. Goering, N. J. Legakis

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Methicillin-resistant Staphylococcus aureus (MRSA) strains isolated over a one-year period from a Greek hospital were tested for their levels of resistance to methicillin by population analysis. Heterogeneously resistant strains belonged to classes I, II, and II/III, whereas homogeneously resistant ones belonged to class IV. Strains of all classes possessed the mecA gene. Pulsed-field gel electrophoresis (PFGE) of Smal-digested genomic DNA revealed that all heterogeneously resistant strains were related. Homogeneously resistant strains were also closely related, but in a cluster distinct from the heterogeneous one. The methicillin-sensitive strains displayed a greater variety of PFGE types compared to MRSA isolates.

Original languageEnglish
Pages (from-to)170-173
Number of pages4
JournalEuropean Journal of Clinical Microbiology and Infectious Diseases
Issue number2
Publication statusPublished - 1997


All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Immunology

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