Distinct genotypic clusters of heterogeneously and homogeneously methicillin-resistant Staphylococcus aureus from a Greek hospital

P. T. Tassios; A. C. Vatopoulos; A. Xanthaki; E. Mainas; R. V. Goering; N. J. Legakis

doi:10.1007/BF01709481

Distinct genotypic clusters of heterogeneously and homogeneously methicillin-resistant Staphylococcus aureus from a Greek hospital

P. T. Tassios, A. C. Vatopoulos, A. Xanthaki, E. Mainas, R. V. Goering, N. J. Legakis

Department of Medical Microbiology and Immunology

Research output: Contribution to journal › Article › peer-review

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Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) strains isolated over a one-year period from a Greek hospital were tested for their levels of resistance to methicillin by population analysis. Heterogeneously resistant strains belonged to classes I, II, and II/III, whereas homogeneously resistant ones belonged to class IV. Strains of all classes possessed the mecA gene. Pulsed-field gel electrophoresis (PFGE) of Smal-digested genomic DNA revealed that all heterogeneously resistant strains were related. Homogeneously resistant strains were also closely related, but in a cluster distinct from the heterogeneous one. The methicillin-sensitive strains displayed a greater variety of PFGE types compared to MRSA isolates.

Original language	English (US)
Pages (from-to)	170-173
Number of pages	4
Journal	European Journal of Clinical Microbiology and Infectious Diseases
Volume	16
Issue number	2
DOIs	https://doi.org/10.1007/BF01709481
State	Published - 1997

All Science Journal Classification (ASJC) codes

Microbiology (medical)
Infectious Diseases

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abstract = "Methicillin-resistant Staphylococcus aureus (MRSA) strains isolated over a one-year period from a Greek hospital were tested for their levels of resistance to methicillin by population analysis. Heterogeneously resistant strains belonged to classes I, II, and II/III, whereas homogeneously resistant ones belonged to class IV. Strains of all classes possessed the mecA gene. Pulsed-field gel electrophoresis (PFGE) of Smal-digested genomic DNA revealed that all heterogeneously resistant strains were related. Homogeneously resistant strains were also closely related, but in a cluster distinct from the heterogeneous one. The methicillin-sensitive strains displayed a greater variety of PFGE types compared to MRSA isolates.",

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AU - Tassios, P. T.

AU - Vatopoulos, A. C.

AU - Xanthaki, A.

AU - Mainas, E.

AU - Goering, R. V.

AU - Legakis, N. J.

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AB - Methicillin-resistant Staphylococcus aureus (MRSA) strains isolated over a one-year period from a Greek hospital were tested for their levels of resistance to methicillin by population analysis. Heterogeneously resistant strains belonged to classes I, II, and II/III, whereas homogeneously resistant ones belonged to class IV. Strains of all classes possessed the mecA gene. Pulsed-field gel electrophoresis (PFGE) of Smal-digested genomic DNA revealed that all heterogeneously resistant strains were related. Homogeneously resistant strains were also closely related, but in a cluster distinct from the heterogeneous one. The methicillin-sensitive strains displayed a greater variety of PFGE types compared to MRSA isolates.

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Distinct genotypic clusters of heterogeneously and homogeneously methicillin-resistant Staphylococcus aureus from a Greek hospital

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