Distribution of calcium absorption in middle-aged women

R. P. Heaney, Robert R. Recker

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

Distribution of true fractional absorption of calcium in estrogen-deprived, nonosteoporotic, middle-aged women was examined in 273 person-studies, using a double-tracer method. Fractional absorption averaged 0.266 (± 0.096). Calcium intake averaged 0.802 g/day (± 0.419) and urine calcium, 0.144 g/day (± 0.062). Fractional absorption was inversely correlated with intake. Using parameters of the regression equation for the two variables, each absorption value was adjusted to the mean intake of the group so that absorption could be evaluated apart from the effect of intake. The distribution of such diet-adjusted values revealed that 55% of these estrogen-deprived women had insufficient absorption to maintain calcium balance at an intake equal to the 1980 RDA. Nearly one-fourth would still be in negative balance at an intake of 1.5 g/day. Since urine calcium was positively correlated with absorbed calcium (r = 0.521), we conclude that defective absorption and not bone breakdown is the basis for low absorptive performance in these women.

Original languageEnglish
Pages (from-to)299-305
Number of pages7
JournalAmerican Journal of Clinical Nutrition
Volume43
Issue number2
StatePublished - 1986

Fingerprint

middle-aged adults
Calcium
calcium
estrogens
Estrogens
urine
Urine
tracer techniques
bones
Diet
Bone and Bones

All Science Journal Classification (ASJC) codes

  • Food Science
  • Medicine (miscellaneous)

Cite this

Distribution of calcium absorption in middle-aged women. / Heaney, R. P.; Recker, Robert R.

In: American Journal of Clinical Nutrition, Vol. 43, No. 2, 1986, p. 299-305.

Research output: Contribution to journalArticle

@article{76cd4dfbd8da498bb0972ba866f942fe,
title = "Distribution of calcium absorption in middle-aged women",
abstract = "Distribution of true fractional absorption of calcium in estrogen-deprived, nonosteoporotic, middle-aged women was examined in 273 person-studies, using a double-tracer method. Fractional absorption averaged 0.266 (± 0.096). Calcium intake averaged 0.802 g/day (± 0.419) and urine calcium, 0.144 g/day (± 0.062). Fractional absorption was inversely correlated with intake. Using parameters of the regression equation for the two variables, each absorption value was adjusted to the mean intake of the group so that absorption could be evaluated apart from the effect of intake. The distribution of such diet-adjusted values revealed that 55{\%} of these estrogen-deprived women had insufficient absorption to maintain calcium balance at an intake equal to the 1980 RDA. Nearly one-fourth would still be in negative balance at an intake of 1.5 g/day. Since urine calcium was positively correlated with absorbed calcium (r = 0.521), we conclude that defective absorption and not bone breakdown is the basis for low absorptive performance in these women.",
author = "Heaney, {R. P.} and Recker, {Robert R.}",
year = "1986",
language = "English",
volume = "43",
pages = "299--305",
journal = "American Journal of Clinical Nutrition",
issn = "0002-9165",
publisher = "American Society for Nutrition",
number = "2",

}

TY - JOUR

T1 - Distribution of calcium absorption in middle-aged women

AU - Heaney, R. P.

AU - Recker, Robert R.

PY - 1986

Y1 - 1986

N2 - Distribution of true fractional absorption of calcium in estrogen-deprived, nonosteoporotic, middle-aged women was examined in 273 person-studies, using a double-tracer method. Fractional absorption averaged 0.266 (± 0.096). Calcium intake averaged 0.802 g/day (± 0.419) and urine calcium, 0.144 g/day (± 0.062). Fractional absorption was inversely correlated with intake. Using parameters of the regression equation for the two variables, each absorption value was adjusted to the mean intake of the group so that absorption could be evaluated apart from the effect of intake. The distribution of such diet-adjusted values revealed that 55% of these estrogen-deprived women had insufficient absorption to maintain calcium balance at an intake equal to the 1980 RDA. Nearly one-fourth would still be in negative balance at an intake of 1.5 g/day. Since urine calcium was positively correlated with absorbed calcium (r = 0.521), we conclude that defective absorption and not bone breakdown is the basis for low absorptive performance in these women.

AB - Distribution of true fractional absorption of calcium in estrogen-deprived, nonosteoporotic, middle-aged women was examined in 273 person-studies, using a double-tracer method. Fractional absorption averaged 0.266 (± 0.096). Calcium intake averaged 0.802 g/day (± 0.419) and urine calcium, 0.144 g/day (± 0.062). Fractional absorption was inversely correlated with intake. Using parameters of the regression equation for the two variables, each absorption value was adjusted to the mean intake of the group so that absorption could be evaluated apart from the effect of intake. The distribution of such diet-adjusted values revealed that 55% of these estrogen-deprived women had insufficient absorption to maintain calcium balance at an intake equal to the 1980 RDA. Nearly one-fourth would still be in negative balance at an intake of 1.5 g/day. Since urine calcium was positively correlated with absorbed calcium (r = 0.521), we conclude that defective absorption and not bone breakdown is the basis for low absorptive performance in these women.

UR - http://www.scopus.com/inward/record.url?scp=0022574844&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022574844&partnerID=8YFLogxK

M3 - Article

VL - 43

SP - 299

EP - 305

JO - American Journal of Clinical Nutrition

JF - American Journal of Clinical Nutrition

SN - 0002-9165

IS - 2

ER -