Abstract
While the use of cocaine in pregnancy continues to be a significant contributor to adverse maternal and perinatal outcomes, systematic study of the physiologic effects of cocaine in human gestation remains difficult. In a case of acute cocaine intoxication in the third trimester, Doppler velocimetry suggested a physiologic response from the uterine artery but not the umbilical artery. Furthermore, the abnormal uterine artery velocimetry was associated with a positive nonreactive contraction stress test, which became negative and reactive as the effects of the cocaine wore off and the velocimetry returned to normal. These observations suggest that the uterine arteries are more sensitive to cocaine than are the umbilical arteries and that abnormal fetal heart rate patterns during acute cocaine intoxication may be transitory.
| Original language | English |
|---|---|
| Pages (from-to) | 65-67 |
| Number of pages | 3 |
| Journal | The Journal of reproductive medicine |
| Volume | 40 |
| Issue number | 1 |
| State | Published - 1995 |
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All Science Journal Classification (ASJC) codes
- Obstetrics and Gynecology
- Reproductive Medicine
Cite this
Doppler velocimetry and fetal heart rate pattern observations in acute cocaine intoxication : A case report. / George, K.; Smith, Jr., James; Curet, L. B.
In: The Journal of reproductive medicine, Vol. 40, No. 1, 1995, p. 65-67.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Doppler velocimetry and fetal heart rate pattern observations in acute cocaine intoxication
T2 - A case report
AU - George, K.
AU - Smith, Jr., James
AU - Curet, L. B.
PY - 1995
Y1 - 1995
N2 - While the use of cocaine in pregnancy continues to be a significant contributor to adverse maternal and perinatal outcomes, systematic study of the physiologic effects of cocaine in human gestation remains difficult. In a case of acute cocaine intoxication in the third trimester, Doppler velocimetry suggested a physiologic response from the uterine artery but not the umbilical artery. Furthermore, the abnormal uterine artery velocimetry was associated with a positive nonreactive contraction stress test, which became negative and reactive as the effects of the cocaine wore off and the velocimetry returned to normal. These observations suggest that the uterine arteries are more sensitive to cocaine than are the umbilical arteries and that abnormal fetal heart rate patterns during acute cocaine intoxication may be transitory.
AB - While the use of cocaine in pregnancy continues to be a significant contributor to adverse maternal and perinatal outcomes, systematic study of the physiologic effects of cocaine in human gestation remains difficult. In a case of acute cocaine intoxication in the third trimester, Doppler velocimetry suggested a physiologic response from the uterine artery but not the umbilical artery. Furthermore, the abnormal uterine artery velocimetry was associated with a positive nonreactive contraction stress test, which became negative and reactive as the effects of the cocaine wore off and the velocimetry returned to normal. These observations suggest that the uterine arteries are more sensitive to cocaine than are the umbilical arteries and that abnormal fetal heart rate patterns during acute cocaine intoxication may be transitory.
UR - http://www.scopus.com/inward/record.url?scp=0028801730&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028801730&partnerID=8YFLogxK
M3 - Article
C2 - 7722980
AN - SCOPUS:0028801730
VL - 40
SP - 65
EP - 67
JO - The Journal of reproductive medicine
JF - The Journal of reproductive medicine
SN - 0024-7758
IS - 1
ER -