Dual-beam laser traps in biology and medicine: When one beam is not enough

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Optical traps are nowadays quite ubiquitous in biophysical and biological studies. The term is often used synonymously with optical tweezers, one particular incarnation of optical traps. However, there is another kind of optical trap consisting of two non-focused, counter-propagating laser beams. This dual-beam trap predates optical tweezers by almost two decades and currently experiences a renaissance. The advantages of dual-beam traps include lower intensities on the trapped object, decoupling from imaging optics, and the possibility to trap cells and cell clusters up to 100 microns in diameter. When used for deforming cells this trap is referred to as an optical stretcher. I will review several applications of such traps in biology and medicine for the detection of cancer cells, sorting stem cells, testing light guiding properties of retinal cells and the controlled rotation of cells for single cell tomography.

Original language	English
Title of host publication	Optical Trapping and Optical Micromanipulation VII
Volume	7762
DOIs	https://doi.org/10.1117/12.862928
Publication status	Published - 2010
Externally published	Yes
Event	Optical Trapping and Optical Micromanipulation VII - San Diego, CA, United States Duration: Aug 1 2010 → Aug 5 2010

Other

Other	Optical Trapping and Optical Micromanipulation VII
Country	United States
City	San Diego, CA
Period	8/1/10 → 8/5/10

Fingerprint

All Science Journal Classification (ASJC) codes

Applied Mathematics
Computer Science Applications
Electrical and Electronic Engineering
Electronic, Optical and Magnetic Materials
Condensed Matter Physics

Cite this

Whyte, G., Lautenschläger, F., Kreysing, M., Boyde, L., Ekpenyong, A., Delabre, U., ... Guck, J. (2010). Dual-beam laser traps in biology and medicine: When one beam is not enough. In Optical Trapping and Optical Micromanipulation VII (Vol. 7762). [77620G] https://doi.org/10.1117/12.862928

Dual-beam laser traps in biology and medicine : When one beam is not enough. / Whyte, Graeme; Lautenschläger, Franziska; Kreysing, Moritz; Boyde, Lars; Ekpenyong, Andrew; Delabre, Ulysse; Chalut, Kevin; Franze, Kristian; Guck, Jochen.

Optical Trapping and Optical Micromanipulation VII. Vol. 7762 2010. 77620G.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

@inproceedings{c925edf5307b4b358cb95dce5848b7a6,

title = "Dual-beam laser traps in biology and medicine: When one beam is not enough",

abstract = "Optical traps are nowadays quite ubiquitous in biophysical and biological studies. The term is often used synonymously with optical tweezers, one particular incarnation of optical traps. However, there is another kind of optical trap consisting of two non-focused, counter-propagating laser beams. This dual-beam trap predates optical tweezers by almost two decades and currently experiences a renaissance. The advantages of dual-beam traps include lower intensities on the trapped object, decoupling from imaging optics, and the possibility to trap cells and cell clusters up to 100 microns in diameter. When used for deforming cells this trap is referred to as an optical stretcher. I will review several applications of such traps in biology and medicine for the detection of cancer cells, sorting stem cells, testing light guiding properties of retinal cells and the controlled rotation of cells for single cell tomography.",

author = "Graeme Whyte and Franziska Lautenschl{\"a}ger and Moritz Kreysing and Lars Boyde and Andrew Ekpenyong and Ulysse Delabre and Kevin Chalut and Kristian Franze and Jochen Guck",

year = "2010",

doi = "10.1117/12.862928",

language = "English",

isbn = "9780819482587",

volume = "7762",

booktitle = "Optical Trapping and Optical Micromanipulation VII",

note = "null ; Conference date: 01-08-2010 Through 05-08-2010",

}

TY - GEN

T1 - Dual-beam laser traps in biology and medicine

AU - Whyte, Graeme

AU - Lautenschläger, Franziska

AU - Kreysing, Moritz

AU - Boyde, Lars

AU - Ekpenyong, Andrew

AU - Delabre, Ulysse

AU - Chalut, Kevin

AU - Franze, Kristian

AU - Guck, Jochen

PY - 2010

Y1 - 2010

N2 - Optical traps are nowadays quite ubiquitous in biophysical and biological studies. The term is often used synonymously with optical tweezers, one particular incarnation of optical traps. However, there is another kind of optical trap consisting of two non-focused, counter-propagating laser beams. This dual-beam trap predates optical tweezers by almost two decades and currently experiences a renaissance. The advantages of dual-beam traps include lower intensities on the trapped object, decoupling from imaging optics, and the possibility to trap cells and cell clusters up to 100 microns in diameter. When used for deforming cells this trap is referred to as an optical stretcher. I will review several applications of such traps in biology and medicine for the detection of cancer cells, sorting stem cells, testing light guiding properties of retinal cells and the controlled rotation of cells for single cell tomography.

AB - Optical traps are nowadays quite ubiquitous in biophysical and biological studies. The term is often used synonymously with optical tweezers, one particular incarnation of optical traps. However, there is another kind of optical trap consisting of two non-focused, counter-propagating laser beams. This dual-beam trap predates optical tweezers by almost two decades and currently experiences a renaissance. The advantages of dual-beam traps include lower intensities on the trapped object, decoupling from imaging optics, and the possibility to trap cells and cell clusters up to 100 microns in diameter. When used for deforming cells this trap is referred to as an optical stretcher. I will review several applications of such traps in biology and medicine for the detection of cancer cells, sorting stem cells, testing light guiding properties of retinal cells and the controlled rotation of cells for single cell tomography.

UR - http://www.scopus.com/inward/record.url?scp=77958130524&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77958130524&partnerID=8YFLogxK

U2 - 10.1117/12.862928

DO - 10.1117/12.862928

M3 - Conference contribution

AN - SCOPUS:77958130524

SN - 9780819482587

VL - 7762

BT - Optical Trapping and Optical Micromanipulation VII

Y2 - 1 August 2010 through 5 August 2010

ER -