Abstract
Optical traps are nowadays quite ubiquitous in biophysical and biological studies. The term is often used synonymously with optical tweezers, one particular incarnation of optical traps. However, there is another kind of optical trap consisting of two non-focused, counter-propagating laser beams. This dual-beam trap predates optical tweezers by almost two decades and currently experiences a renaissance. The advantages of dual-beam traps include lower intensities on the trapped object, decoupling from imaging optics, and the possibility to trap cells and cell clusters up to 100 microns in diameter. When used for deforming cells this trap is referred to as an optical stretcher. I will review several applications of such traps in biology and medicine for the detection of cancer cells, sorting stem cells, testing light guiding properties of retinal cells and the controlled rotation of cells for single cell tomography.
| Original language | English |
|---|---|
| Title of host publication | Optical Trapping and Optical Micromanipulation VII |
| Volume | 7762 |
| DOIs | |
| State | Published - 2010 |
| Externally published | Yes |
| Event | Optical Trapping and Optical Micromanipulation VII - San Diego, CA, United States Duration: Aug 1 2010 → Aug 5 2010 |
Other
| Other | Optical Trapping and Optical Micromanipulation VII |
|---|---|
| Country | United States |
| City | San Diego, CA |
| Period | 8/1/10 → 8/5/10 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Applied Mathematics
- Computer Science Applications
- Electrical and Electronic Engineering
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
Cite this
Dual-beam laser traps in biology and medicine : When one beam is not enough. / Whyte, Graeme; Lautenschläger, Franziska; Kreysing, Moritz; Boyde, Lars; Ekpenyong, Andrew; Delabre, Ulysse; Chalut, Kevin; Franze, Kristian; Guck, Jochen.
Optical Trapping and Optical Micromanipulation VII. Vol. 7762 2010. 77620G.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Dual-beam laser traps in biology and medicine
T2 - When one beam is not enough
AU - Whyte, Graeme
AU - Lautenschläger, Franziska
AU - Kreysing, Moritz
AU - Boyde, Lars
AU - Ekpenyong, Andrew
AU - Delabre, Ulysse
AU - Chalut, Kevin
AU - Franze, Kristian
AU - Guck, Jochen
PY - 2010
Y1 - 2010
N2 - Optical traps are nowadays quite ubiquitous in biophysical and biological studies. The term is often used synonymously with optical tweezers, one particular incarnation of optical traps. However, there is another kind of optical trap consisting of two non-focused, counter-propagating laser beams. This dual-beam trap predates optical tweezers by almost two decades and currently experiences a renaissance. The advantages of dual-beam traps include lower intensities on the trapped object, decoupling from imaging optics, and the possibility to trap cells and cell clusters up to 100 microns in diameter. When used for deforming cells this trap is referred to as an optical stretcher. I will review several applications of such traps in biology and medicine for the detection of cancer cells, sorting stem cells, testing light guiding properties of retinal cells and the controlled rotation of cells for single cell tomography.
AB - Optical traps are nowadays quite ubiquitous in biophysical and biological studies. The term is often used synonymously with optical tweezers, one particular incarnation of optical traps. However, there is another kind of optical trap consisting of two non-focused, counter-propagating laser beams. This dual-beam trap predates optical tweezers by almost two decades and currently experiences a renaissance. The advantages of dual-beam traps include lower intensities on the trapped object, decoupling from imaging optics, and the possibility to trap cells and cell clusters up to 100 microns in diameter. When used for deforming cells this trap is referred to as an optical stretcher. I will review several applications of such traps in biology and medicine for the detection of cancer cells, sorting stem cells, testing light guiding properties of retinal cells and the controlled rotation of cells for single cell tomography.
UR - http://www.scopus.com/inward/record.url?scp=77958130524&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77958130524&partnerID=8YFLogxK
U2 - 10.1117/12.862928
DO - 10.1117/12.862928
M3 - Conference contribution
SN - 9780819482587
VL - 7762
BT - Optical Trapping and Optical Micromanipulation VII
ER -