TY - JOUR
T1 - Effect of a barley breakfast cereal on blood glucose and insulin response in normal and diabetic patients
AU - Rendell, M.
AU - Vanderhoof, J.
AU - Venn, M.
AU - Shehan, M. A.
AU - Arndt, E.
AU - Rao, C. S.
AU - Gill, G.
AU - Newman, R. K.
AU - Newman, C. W.
N1 - Funding Information:
This work was supported by a grant from the ConAgra Grain Processing Company, Omaha, NE.
PY - 2005/6
Y1 - 2005/6
N2 - Prowashonupana (Prowash) is a shrunken-endosperm, short awn, waxy starch, hulless barley with low starch, high fiber, high protein, and a relatively high concentration of free sugars. The study was designed to compare equivalent breakfast meals (w/w) of Prowash and oatmeal for glycemic response in diabetic and non-diabetic subjects. A commercial liquid meal replacer (LMR) was included as a reference standard. A substantial reduction of the post-prandial glycemic peak following ingestion of Prowash was observed as compared to LMR or oatmeal. In the non-diabetic subjects, the maximal rise in glucose from baseline was 26.3± 3.9 mg/dL after LMR, 41.3± 3.9 mg/dL after oatmeal and 6.4± 2.7 mg/dL after Prowash (p <0.01). The maximal increase in glucose in the diabetic patients was 69.9± 4.5 mg/dL after LMR, 80.8± 8.8,mg/dL after oatmeal and 28.4± 3.5 mg/dL after Prowash (p <0.01). The maximal increase in insulin post-LMR was 33.9± 3.6 mIU/ml in the diabetic patients and 54.0± 9.8,mIU/ml in the non-diabetic controls. Oatmeal elicited a maximal insulin increase of 29.9± 4.2, mIU/ml in the control subjects and 21.4± 2.5 mIU/ml in the diabetic patients. In contrast, the maximal insulin increase after Prowash was 8.6± 1.5 mIU/ml in the non-diabetic controls and 6.8± 1.2 mIU/ml in the diabetic patients (p <0.01).
AB - Prowashonupana (Prowash) is a shrunken-endosperm, short awn, waxy starch, hulless barley with low starch, high fiber, high protein, and a relatively high concentration of free sugars. The study was designed to compare equivalent breakfast meals (w/w) of Prowash and oatmeal for glycemic response in diabetic and non-diabetic subjects. A commercial liquid meal replacer (LMR) was included as a reference standard. A substantial reduction of the post-prandial glycemic peak following ingestion of Prowash was observed as compared to LMR or oatmeal. In the non-diabetic subjects, the maximal rise in glucose from baseline was 26.3± 3.9 mg/dL after LMR, 41.3± 3.9 mg/dL after oatmeal and 6.4± 2.7 mg/dL after Prowash (p <0.01). The maximal increase in glucose in the diabetic patients was 69.9± 4.5 mg/dL after LMR, 80.8± 8.8,mg/dL after oatmeal and 28.4± 3.5 mg/dL after Prowash (p <0.01). The maximal increase in insulin post-LMR was 33.9± 3.6 mIU/ml in the diabetic patients and 54.0± 9.8,mIU/ml in the non-diabetic controls. Oatmeal elicited a maximal insulin increase of 29.9± 4.2, mIU/ml in the control subjects and 21.4± 2.5 mIU/ml in the diabetic patients. In contrast, the maximal insulin increase after Prowash was 8.6± 1.5 mIU/ml in the non-diabetic controls and 6.8± 1.2 mIU/ml in the diabetic patients (p <0.01).
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U2 - 10.1007/s11130-005-5101-8
DO - 10.1007/s11130-005-5101-8
M3 - Article
C2 - 16021833
AN - SCOPUS:22144450005
VL - 60
SP - 63
EP - 67
JO - Plant Foods for Human Nutrition
JF - Plant Foods for Human Nutrition
SN - 0921-9668
IS - 2
ER -