Abstract
Adenosine and pertussis vaccine each significantly suppresed the in vitro lymphocyte response to photohemagglutinin (PHA) in both asthmatic and non-asthmatic subjects. On the other hand, pertussis vaccine significantly enhanced the response of the lymphocytes treated with a lower concentration of adenosine both in asthmatic and non-asthmatic subjects. It was also shown that lymphocytes from asthmatic and non-asthmatic subjects responded similarly to the modulating effect of adenosine and/or pertussis vaccine on PHA stimulation. These data give further evidence for the complex interplay of the vaccine with endogenous adenosine.
| Original language | English |
|---|---|
| Pages (from-to) | 142-146 |
| Number of pages | 5 |
| Journal | Annals of Allergy |
| Volume | 61 |
| Issue number | 2 |
| State | Published - 1988 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Immunology and Allergy
Cite this
Effect of adenosine and pertussis vaccine on lymphocyte response in vitro to phytohemmaglutinin in asthmatic and non-asthmatic subjects. / Hiratani, M.; McCall, M. K.; Chaperon, E. A.; Townley, R. G.
In: Annals of Allergy, Vol. 61, No. 2, 1988, p. 142-146.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effect of adenosine and pertussis vaccine on lymphocyte response in vitro to phytohemmaglutinin in asthmatic and non-asthmatic subjects
AU - Hiratani, M.
AU - McCall, M. K.
AU - Chaperon, E. A.
AU - Townley, R. G.
PY - 1988
Y1 - 1988
N2 - Adenosine and pertussis vaccine each significantly suppresed the in vitro lymphocyte response to photohemagglutinin (PHA) in both asthmatic and non-asthmatic subjects. On the other hand, pertussis vaccine significantly enhanced the response of the lymphocytes treated with a lower concentration of adenosine both in asthmatic and non-asthmatic subjects. It was also shown that lymphocytes from asthmatic and non-asthmatic subjects responded similarly to the modulating effect of adenosine and/or pertussis vaccine on PHA stimulation. These data give further evidence for the complex interplay of the vaccine with endogenous adenosine.
AB - Adenosine and pertussis vaccine each significantly suppresed the in vitro lymphocyte response to photohemagglutinin (PHA) in both asthmatic and non-asthmatic subjects. On the other hand, pertussis vaccine significantly enhanced the response of the lymphocytes treated with a lower concentration of adenosine both in asthmatic and non-asthmatic subjects. It was also shown that lymphocytes from asthmatic and non-asthmatic subjects responded similarly to the modulating effect of adenosine and/or pertussis vaccine on PHA stimulation. These data give further evidence for the complex interplay of the vaccine with endogenous adenosine.
UR - http://www.scopus.com/inward/record.url?scp=0023706619&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023706619&partnerID=8YFLogxK
M3 - Article
VL - 61
SP - 142
EP - 146
JO - Annals of Allergy, Asthma and Immunology
JF - Annals of Allergy, Asthma and Immunology
SN - 1081-1206
IS - 2
ER -