Effect of creatine phosphate supplementation on anaerobic working capacity and body weight after two and six days of loading in men and women

Joan M. Eckerson, Jeffrey R. Stout, Geri A. Moore, Nancy J. Stone, Kate A. Iwan, Amy N. Gebauer, Rachelle Ginsberg

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25 Scopus citations


The purpose of this study was to determine the effects of 2 and 6 days of creatine phosphate loading on anaerobic working capacity (AWC) and body weight (BW) in men and women. Sixty-one men (n = 31) and women (n = 30) randomly received 1 of 3 treatments (4 x 5 g·d-1 x 6 days) using a double blind design: (a) 18 g dextrose as placebo (PL); (b) 5.0 g Cr + 20 g dextrose (Cr); or (c) 5.0 g Cr + 18 g dextrose + 4 g of sodium and potassium phosphates (CrP). AWC was determined at baseline and following 2 and 6 days of supplementation using the Critical Power Test. BW increased significantly over time, and the mean value for the men was significantly greater compared to that for women, but there were no interactions (p > 0.05). There were gender-specific responses for AWC expressed in both absolute values (kJ) and relative to BW (kJ·kg-1), with the women demonstrating no significant interactions. For the men, CrP loading significantly increased AWC following 2 days (23.8%) and 6 days (49.8%) of supplementation vs. PL (kJ and kJ·kg-1). Cr supplementation increased AWC 13-15% in both genders compared to PL (1.1%-3.0% decline); although this result was not statistically significant, it may have some practical significance.

Original languageEnglish (US)
Pages (from-to)756-763
Number of pages8
JournalJournal of strength and conditioning research
Issue number4
StatePublished - Nov 1 2005


All Science Journal Classification (ASJC) codes

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

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