Effect of exercise intensity on active and passive glucose absorption

James A. Lang, Carl V. Gisolfi, G. Patrick Lambert

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

The purpose of this study was to determine the effects of exercise intensity on active and passive intestinal glucose absorption. Eight trained runners (age = 23 ± 2 y; VO2max = 62.1 ± 5.8 mL·kg-1·min-1) performed a 1 h resting experiment and three 1 h treadmill experiments at 30, 50, or 70% VO 2max in a thermoneutral environment. Immediately prior to each experiment, euhydrated subjects ingested a solution containing two non-metabolizable glucose analogs, 3-O-methyl-D-glucose (3MG; actively absorbed; 5 g) and D-xylose (passively absorbed; 5 g). During the following 5 h, all urine was collected and the amount of 3MG and D-xylose in the urine was determined. Using repeated measures ANOVA, a significant (P < 0.05) reduction in urinary excretion of each carbohydrate was observed at 70% VO2max compared to the other intensities suggesting that both active and passive intestinal absorption of glucose may be reduced during prolonged running at this intensity.

Original languageEnglish (US)
Pages (from-to)485-493
Number of pages9
JournalInternational Journal of Sport Nutrition and Exercise Metabolism
Volume16
Issue number5
DOIs
StatePublished - Jan 1 2006

Fingerprint

Xylose
Intestinal Absorption
Glucose
Urine
3-O-Methylglucose
Analysis of Variance
Carbohydrates

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Orthopedics and Sports Medicine
  • Nutrition and Dietetics

Cite this

Effect of exercise intensity on active and passive glucose absorption. / Lang, James A.; Gisolfi, Carl V.; Lambert, G. Patrick.

In: International Journal of Sport Nutrition and Exercise Metabolism, Vol. 16, No. 5, 01.01.2006, p. 485-493.

Research output: Contribution to journalArticle

@article{f6828740d1d9435f8c860105a9b06a3f,
title = "Effect of exercise intensity on active and passive glucose absorption",
abstract = "The purpose of this study was to determine the effects of exercise intensity on active and passive intestinal glucose absorption. Eight trained runners (age = 23 ± 2 y; VO2max = 62.1 ± 5.8 mL·kg-1·min-1) performed a 1 h resting experiment and three 1 h treadmill experiments at 30, 50, or 70{\%} VO 2max in a thermoneutral environment. Immediately prior to each experiment, euhydrated subjects ingested a solution containing two non-metabolizable glucose analogs, 3-O-methyl-D-glucose (3MG; actively absorbed; 5 g) and D-xylose (passively absorbed; 5 g). During the following 5 h, all urine was collected and the amount of 3MG and D-xylose in the urine was determined. Using repeated measures ANOVA, a significant (P < 0.05) reduction in urinary excretion of each carbohydrate was observed at 70{\%} VO2max compared to the other intensities suggesting that both active and passive intestinal absorption of glucose may be reduced during prolonged running at this intensity.",
author = "Lang, {James A.} and Gisolfi, {Carl V.} and Lambert, {G. Patrick}",
year = "2006",
month = "1",
day = "1",
doi = "10.1123/ijsnem.16.5.485",
language = "English (US)",
volume = "16",
pages = "485--493",
journal = "International Journal of Sport Nutrition and Exercise Metabolism",
issn = "1526-484X",
publisher = "Human Kinetics Publishers Inc.",
number = "5",

}

TY - JOUR

T1 - Effect of exercise intensity on active and passive glucose absorption

AU - Lang, James A.

AU - Gisolfi, Carl V.

AU - Lambert, G. Patrick

PY - 2006/1/1

Y1 - 2006/1/1

N2 - The purpose of this study was to determine the effects of exercise intensity on active and passive intestinal glucose absorption. Eight trained runners (age = 23 ± 2 y; VO2max = 62.1 ± 5.8 mL·kg-1·min-1) performed a 1 h resting experiment and three 1 h treadmill experiments at 30, 50, or 70% VO 2max in a thermoneutral environment. Immediately prior to each experiment, euhydrated subjects ingested a solution containing two non-metabolizable glucose analogs, 3-O-methyl-D-glucose (3MG; actively absorbed; 5 g) and D-xylose (passively absorbed; 5 g). During the following 5 h, all urine was collected and the amount of 3MG and D-xylose in the urine was determined. Using repeated measures ANOVA, a significant (P < 0.05) reduction in urinary excretion of each carbohydrate was observed at 70% VO2max compared to the other intensities suggesting that both active and passive intestinal absorption of glucose may be reduced during prolonged running at this intensity.

AB - The purpose of this study was to determine the effects of exercise intensity on active and passive intestinal glucose absorption. Eight trained runners (age = 23 ± 2 y; VO2max = 62.1 ± 5.8 mL·kg-1·min-1) performed a 1 h resting experiment and three 1 h treadmill experiments at 30, 50, or 70% VO 2max in a thermoneutral environment. Immediately prior to each experiment, euhydrated subjects ingested a solution containing two non-metabolizable glucose analogs, 3-O-methyl-D-glucose (3MG; actively absorbed; 5 g) and D-xylose (passively absorbed; 5 g). During the following 5 h, all urine was collected and the amount of 3MG and D-xylose in the urine was determined. Using repeated measures ANOVA, a significant (P < 0.05) reduction in urinary excretion of each carbohydrate was observed at 70% VO2max compared to the other intensities suggesting that both active and passive intestinal absorption of glucose may be reduced during prolonged running at this intensity.

UR - http://www.scopus.com/inward/record.url?scp=33749476049&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33749476049&partnerID=8YFLogxK

U2 - 10.1123/ijsnem.16.5.485

DO - 10.1123/ijsnem.16.5.485

M3 - Article

C2 - 17240781

AN - SCOPUS:33749476049

VL - 16

SP - 485

EP - 493

JO - International Journal of Sport Nutrition and Exercise Metabolism

JF - International Journal of Sport Nutrition and Exercise Metabolism

SN - 1526-484X

IS - 5

ER -