Effect of exercise intensity on active and passive glucose absorption

James A. Lang, Carl V. Gisolfi, G. Patrick Lambert

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

The purpose of this study was to determine the effects of exercise intensity on active and passive intestinal glucose absorption. Eight trained runners (age = 23 ± 2 y; VO2max = 62.1 ± 5.8 mL·kg-1·min-1) performed a 1 h resting experiment and three 1 h treadmill experiments at 30, 50, or 70% VO 2max in a thermoneutral environment. Immediately prior to each experiment, euhydrated subjects ingested a solution containing two non-metabolizable glucose analogs, 3-O-methyl-D-glucose (3MG; actively absorbed; 5 g) and D-xylose (passively absorbed; 5 g). During the following 5 h, all urine was collected and the amount of 3MG and D-xylose in the urine was determined. Using repeated measures ANOVA, a significant (P < 0.05) reduction in urinary excretion of each carbohydrate was observed at 70% VO2max compared to the other intensities suggesting that both active and passive intestinal absorption of glucose may be reduced during prolonged running at this intensity.

Original languageEnglish (US)
Pages (from-to)485-493
Number of pages9
JournalInternational Journal of Sport Nutrition and Exercise Metabolism
Volume16
Issue number5
DOIs
StatePublished - Jan 1 2006

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Orthopedics and Sports Medicine
  • Nutrition and Dietetics

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