Effect of growth hormone on skeletal mass in adult dogs

William H. Harris; Robert P. Heaney

doi:10.1038/223403a0

Effect of growth hormone on skeletal mass in adult dogs

William H. Harris, Robert P. Heaney

Department of Medicine

Research output: Contribution to journal › Letter › peer-review

64 Scopus citations

Abstract

THE skeletal mass of adult dogs of both sexes can be significantly increased by administering exogenous bovine growth hormone (0.5 mg/kg/day for 84 days) without inducing acromegaly or diabetes. This increase is a consequence of a marked rise in new bone formation. The new bone is histologically and microradiographically normal.

Original language	English (US)
Pages (from-to)	403-404
Number of pages	2
Journal	Nature
Volume	223
Issue number	5204
DOIs	https://doi.org/10.1038/223403a0
State	Published - 1969

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title = "Effect of growth hormone on skeletal mass in adult dogs",

abstract = "THE skeletal mass of adult dogs of both sexes can be significantly increased by administering exogenous bovine growth hormone (0.5 mg/kg/day for 84 days) without inducing acromegaly or diabetes. This increase is a consequence of a marked rise in new bone formation. The new bone is histologically and microradiographically normal.",

author = "Harris, {William H.} and Heaney, {Robert P.}",

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doi = "10.1038/223403a0",

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T1 - Effect of growth hormone on skeletal mass in adult dogs

AU - Harris, William H.

AU - Heaney, Robert P.

PY - 1969

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N2 - THE skeletal mass of adult dogs of both sexes can be significantly increased by administering exogenous bovine growth hormone (0.5 mg/kg/day for 84 days) without inducing acromegaly or diabetes. This increase is a consequence of a marked rise in new bone formation. The new bone is histologically and microradiographically normal.

AB - THE skeletal mass of adult dogs of both sexes can be significantly increased by administering exogenous bovine growth hormone (0.5 mg/kg/day for 84 days) without inducing acromegaly or diabetes. This increase is a consequence of a marked rise in new bone formation. The new bone is histologically and microradiographically normal.

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U2 - 10.1038/223403a0

DO - 10.1038/223403a0

M3 - Letter

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EP - 404

JO - Nature

JF - Nature

SN - 0028-0836

IS - 5204

ER -

Effect of growth hormone on skeletal mass in adult dogs

Abstract

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