Abstract
To investigate in vitro the interaction of seven fluoroquinolone antibiotics with the determination of serum creatinine by the picric acid and enzymatic methods. This blind, in vitro study assayed duplicate serum samples for creatinine by the picric acid and enzymatic methods with averaged spiked concentrations of 2.71, 13.56, 27.12, and 108.47 μmol/L of ciprofloxacin, fleroxacin, lomefloxacin, ofloxacin, 1-ofloxacin, sparfloxacin, and temafloxacin. Cefoxitin (in concentrations of 233.9, 1169.6, 1754.4, and 2339.2 μmol/L) was used as a positive control for the picric acid assay. University-affiliated hospital, Department of Pharmaceutical Services and Clinical Chemistry section of the Department of Pathology. The serum creatinine samples spiked with the seven substituted fluoroquinolones and cefoxitin were assayed by both the picric acid and enzymatic assays. Statistical analysis compared the spiked samples with blank serum by Student's t-test and concentration ranges were compared by analysis of variance. A statistically significant interference with serum creatinine was p
| Original language | English |
|---|---|
| Pages (from-to) | 586-588 |
| Number of pages | 3 |
| Journal | Annals of Pharmacotherapy |
| Volume | 27 |
| Issue number | 5 |
| DOIs |
|
| State | Published - 1993 |
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All Science Journal Classification (ASJC) codes
- Pharmacology (medical)
- Pharmacology, Toxicology and Pharmaceutics(all)
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Effect of seven fluoroquinolones on the determination of serum creatinine by the picric acid and enzymatic methods. / Massoomi, Firouzan; Mathews, Herbert G.; Destache, Christopher J.
In: Annals of Pharmacotherapy, Vol. 27, No. 5, 1993, p. 586-588.Research output: Contribution to journal › Comment/debate
}
TY - JOUR
T1 - Effect of seven fluoroquinolones on the determination of serum creatinine by the picric acid and enzymatic methods
AU - Massoomi, Firouzan
AU - Mathews, Herbert G.
AU - Destache, Christopher J.
PY - 1993
Y1 - 1993
N2 - To investigate in vitro the interaction of seven fluoroquinolone antibiotics with the determination of serum creatinine by the picric acid and enzymatic methods. This blind, in vitro study assayed duplicate serum samples for creatinine by the picric acid and enzymatic methods with averaged spiked concentrations of 2.71, 13.56, 27.12, and 108.47 μmol/L of ciprofloxacin, fleroxacin, lomefloxacin, ofloxacin, 1-ofloxacin, sparfloxacin, and temafloxacin. Cefoxitin (in concentrations of 233.9, 1169.6, 1754.4, and 2339.2 μmol/L) was used as a positive control for the picric acid assay. University-affiliated hospital, Department of Pharmaceutical Services and Clinical Chemistry section of the Department of Pathology. The serum creatinine samples spiked with the seven substituted fluoroquinolones and cefoxitin were assayed by both the picric acid and enzymatic assays. Statistical analysis compared the spiked samples with blank serum by Student's t-test and concentration ranges were compared by analysis of variance. A statistically significant interference with serum creatinine was p
AB - To investigate in vitro the interaction of seven fluoroquinolone antibiotics with the determination of serum creatinine by the picric acid and enzymatic methods. This blind, in vitro study assayed duplicate serum samples for creatinine by the picric acid and enzymatic methods with averaged spiked concentrations of 2.71, 13.56, 27.12, and 108.47 μmol/L of ciprofloxacin, fleroxacin, lomefloxacin, ofloxacin, 1-ofloxacin, sparfloxacin, and temafloxacin. Cefoxitin (in concentrations of 233.9, 1169.6, 1754.4, and 2339.2 μmol/L) was used as a positive control for the picric acid assay. University-affiliated hospital, Department of Pharmaceutical Services and Clinical Chemistry section of the Department of Pathology. The serum creatinine samples spiked with the seven substituted fluoroquinolones and cefoxitin were assayed by both the picric acid and enzymatic assays. Statistical analysis compared the spiked samples with blank serum by Student's t-test and concentration ranges were compared by analysis of variance. A statistically significant interference with serum creatinine was p
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UR - http://www.scopus.com/inward/citedby.url?scp=0027262390&partnerID=8YFLogxK
U2 - 10.1177/106002809302700512
DO - 10.1177/106002809302700512
M3 - Comment/debate
VL - 27
SP - 586
EP - 588
JO - Annals of Pharmacotherapy
JF - Annals of Pharmacotherapy
SN - 1060-0280
IS - 5
ER -