Effects of caffeine on circaseptan rhythmicity following surgery in laboratory rats

L. Farr, Catherine Todero, L. Boen

Research output: Contribution to journalArticle


Twenty-four male rats were implanted with radio-transmitters. After recovery, core temperature was monitored with radio-telemetry. Circadian and circaseptan rhythms were analyzed during recovery in rats pretreated with caffeine and in control animals. Data were analyzed using cosinor analysis and comparisons between groups were made with binomial frequency distribution. Fewer rats that received caffeine developed circaseptan rhythms than did control rats suggesting that caffeine reduces circaseptan rhythms following surgery.

Original languageEnglish
Pages (from-to)189-192
Number of pages4
JournalAnnual Review of Chronopharmacology
Publication statusPublished - 1990
Externally publishedYes


All Science Journal Classification (ASJC) codes

  • Pharmacology

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