Effects of chronic histamine and ovalbumin aerosols on pulmonary beta adrenergic receptors in sensitized guinea pigs

J. B. Cheng, R. G. Townley

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Using (3H)dihydroalprenolol, we demonstrated that the concentration of pulmonary beta adrenergic receptor binding sites was lower in guinea pigs showing a marked bronchoconstrictive response to histamine and in ovalbumin-treated guinea pigs. This result suggests that the changed concentration of the pulmonary beta receptors in an animal model of asthma could result from bronchoconstriction stress.

Original languageEnglish (US)
Pages (from-to)507-510
Number of pages4
JournalResearch Communications in Chemical Pathology and Pharmacology
Volume36
Issue number3
StatePublished - Jan 1 1982

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Toxicology
  • Pharmacology
  • Pharmacology, Toxicology and Pharmaceutics(all)

Fingerprint Dive into the research topics of 'Effects of chronic histamine and ovalbumin aerosols on pulmonary beta adrenergic receptors in sensitized guinea pigs'. Together they form a unique fingerprint.

  • Cite this