Effects of chronic histamine and ovalbumin aerosols on pulmonary beta adrenergic receptors in sensitized guinea pigs

J. B. Cheng, R. G. Townley

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Using (3H)dihydroalprenolol, we demonstrated that the concentration of pulmonary beta adrenergic receptor binding sites was lower in guinea pigs showing a marked bronchoconstrictive response to histamine and in ovalbumin-treated guinea pigs. This result suggests that the changed concentration of the pulmonary beta receptors in an animal model of asthma could result from bronchoconstriction stress.

Original languageEnglish
Pages (from-to)507-510
Number of pages4
JournalResearch Communications in Chemical Pathology and Pharmacology
Volume36
Issue number3
StatePublished - 1982

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Dihydroalprenolol
Receptors, Adrenergic, beta
Ovalbumin
Aerosols
Histamine
Guinea Pigs
Animals
Binding Sites
Lung
Bronchoconstriction
Asthma
Animal Models

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Toxicology

Cite this

Effects of chronic histamine and ovalbumin aerosols on pulmonary beta adrenergic receptors in sensitized guinea pigs. / Cheng, J. B.; Townley, R. G.

In: Research Communications in Chemical Pathology and Pharmacology, Vol. 36, No. 3, 1982, p. 507-510.

Research output: Contribution to journalArticle

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