Effects of feed restriction and realimentation on digestive and immune function in the leghorn chick

Carol Fassbinder-Orth, W. H. Karasov

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

How regulatory changes of digestive and immune functions of the gut influence each other has not been sufficiently studied. We tested for simultaneous changes in the digestive physiology and mucosal immune function of the guts of White Leghorn cockerel chicks undergoing food restriction and realimentation. Chicks were assigned to 1 of 3 groups: control = fed ad libitum 7 to 17 d of age; restricted = feed restricted d 12 to 17 (at 2 restriction levels: 54 and 34% ad libitum); refed = feed restricted d 7 to 13 and then fed ad libitum d 14 to 17. Refed chicks exhibited 1 d of hyperphagy and an increase in apparent digestive efficiency following restriction (ANOVA, P <0.001). Total small intestine mass and duodenal maltase activity differed among the groups in the order refed > control > restricted, as expected (ANOVA, P <0.05 for both measures). In contrast, there were no significant treatment effects on our measures of gut immune structure and function, including bursa mass, spleen mass, and total IgA content of intestinal flush samples measured with standard ELISA techniques. The results of this study indicated that, during feed restriction and realimentation, some features of gut immune function are maintained unchanged in the face of regulatory changes that influence digestive functions.

Original languageEnglish
Pages (from-to)1449-1456
Number of pages8
JournalPoultry Science
Volume85
Issue number8
StatePublished - 2006
Externally publishedYes

Fingerprint

repletion
restricted feeding
digestive system
chicks
analysis of variance
digestive physiology
cockerels
White Leghorn
spleen
enzyme-linked immunosorbent assay
sampling
methodology

All Science Journal Classification (ASJC) codes

  • Animal Science and Zoology

Cite this

Effects of feed restriction and realimentation on digestive and immune function in the leghorn chick. / Fassbinder-Orth, Carol; Karasov, W. H.

In: Poultry Science, Vol. 85, No. 8, 2006, p. 1449-1456.

Research output: Contribution to journalArticle

@article{6bf7e8ce03634d1a8e6b813252cbff32,
title = "Effects of feed restriction and realimentation on digestive and immune function in the leghorn chick",
abstract = "How regulatory changes of digestive and immune functions of the gut influence each other has not been sufficiently studied. We tested for simultaneous changes in the digestive physiology and mucosal immune function of the guts of White Leghorn cockerel chicks undergoing food restriction and realimentation. Chicks were assigned to 1 of 3 groups: control = fed ad libitum 7 to 17 d of age; restricted = feed restricted d 12 to 17 (at 2 restriction levels: 54 and 34{\%} ad libitum); refed = feed restricted d 7 to 13 and then fed ad libitum d 14 to 17. Refed chicks exhibited 1 d of hyperphagy and an increase in apparent digestive efficiency following restriction (ANOVA, P <0.001). Total small intestine mass and duodenal maltase activity differed among the groups in the order refed > control > restricted, as expected (ANOVA, P <0.05 for both measures). In contrast, there were no significant treatment effects on our measures of gut immune structure and function, including bursa mass, spleen mass, and total IgA content of intestinal flush samples measured with standard ELISA techniques. The results of this study indicated that, during feed restriction and realimentation, some features of gut immune function are maintained unchanged in the face of regulatory changes that influence digestive functions.",
author = "Carol Fassbinder-Orth and Karasov, {W. H.}",
year = "2006",
language = "English",
volume = "85",
pages = "1449--1456",
journal = "Poultry Science",
issn = "0032-5791",
publisher = "Poultry Science Association",
number = "8",

}

TY - JOUR

T1 - Effects of feed restriction and realimentation on digestive and immune function in the leghorn chick

AU - Fassbinder-Orth, Carol

AU - Karasov, W. H.

PY - 2006

Y1 - 2006

N2 - How regulatory changes of digestive and immune functions of the gut influence each other has not been sufficiently studied. We tested for simultaneous changes in the digestive physiology and mucosal immune function of the guts of White Leghorn cockerel chicks undergoing food restriction and realimentation. Chicks were assigned to 1 of 3 groups: control = fed ad libitum 7 to 17 d of age; restricted = feed restricted d 12 to 17 (at 2 restriction levels: 54 and 34% ad libitum); refed = feed restricted d 7 to 13 and then fed ad libitum d 14 to 17. Refed chicks exhibited 1 d of hyperphagy and an increase in apparent digestive efficiency following restriction (ANOVA, P <0.001). Total small intestine mass and duodenal maltase activity differed among the groups in the order refed > control > restricted, as expected (ANOVA, P <0.05 for both measures). In contrast, there were no significant treatment effects on our measures of gut immune structure and function, including bursa mass, spleen mass, and total IgA content of intestinal flush samples measured with standard ELISA techniques. The results of this study indicated that, during feed restriction and realimentation, some features of gut immune function are maintained unchanged in the face of regulatory changes that influence digestive functions.

AB - How regulatory changes of digestive and immune functions of the gut influence each other has not been sufficiently studied. We tested for simultaneous changes in the digestive physiology and mucosal immune function of the guts of White Leghorn cockerel chicks undergoing food restriction and realimentation. Chicks were assigned to 1 of 3 groups: control = fed ad libitum 7 to 17 d of age; restricted = feed restricted d 12 to 17 (at 2 restriction levels: 54 and 34% ad libitum); refed = feed restricted d 7 to 13 and then fed ad libitum d 14 to 17. Refed chicks exhibited 1 d of hyperphagy and an increase in apparent digestive efficiency following restriction (ANOVA, P <0.001). Total small intestine mass and duodenal maltase activity differed among the groups in the order refed > control > restricted, as expected (ANOVA, P <0.05 for both measures). In contrast, there were no significant treatment effects on our measures of gut immune structure and function, including bursa mass, spleen mass, and total IgA content of intestinal flush samples measured with standard ELISA techniques. The results of this study indicated that, during feed restriction and realimentation, some features of gut immune function are maintained unchanged in the face of regulatory changes that influence digestive functions.

UR - http://www.scopus.com/inward/record.url?scp=33748374225&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33748374225&partnerID=8YFLogxK

M3 - Article

VL - 85

SP - 1449

EP - 1456

JO - Poultry Science

JF - Poultry Science

SN - 0032-5791

IS - 8

ER -