Abstract
Context: Motoneuron-pool facilitation after cryotherapy may be mediated by stimulation of thermoreceptors surrounding a joint. It is unknown whether menthol counterirritants, which also stimulate thermoreceptors, have the same effect on motoneuron-pool excitability (MNPE). Objective: To compare quadriceps MNPE after a menthol-counterirritant application to the anterior knee, a sham counterirritant application, and a control treatment in healthy subjects. Design: A blinded, randomized controlled laboratory study. Setting: Laboratory. Participants: Thirty healthy subjects (16 m, 14 f; 24.1 ± 3.9 y, 170.6 ± 11.4 cm, 72.1 ± 15.6 kg) with no history of lower extremity surgery volunteered for this study. Intervention: Two milliliters of menthol or sham counterirritant was applied to the anterior knee; control subjects received no intervention. Main Outcome Measures: The average vastus medialis normalized Hoffmann reflex (Hmax:Mmax ratio) was used to measure MNPE. Measurements were recorded at 5, 15, 25, and 35 minutes postintervention and compared with baseline measures. Results: Hmax:Mmax ratios for all groups significantly decreased over time (F4,108 = 10.52, P <.001; menthol: baseline = .32 ± .20, 5 min = .29 ± .18, 15 min = .27 ± .18, 25 min = .28 ± .19, 35 min = .27 ± .18; sham: baseline = .46 ± .26, 5 min = .36 ± .20, 15 min = .35 ± .19, 25 min = .35 ± .20, 35 min = .34 ± .18; control: baseline = .48 ± .32, 5 min = .37 ± .27, 15 min = .37 ± .27, 25 min = .37 ± .29, 35 min = .35 ±.28). No significant Group × Time interaction or group differences in Hmax:Mmax were found. Conclusions: Menthol did not affect quadriceps MNPE in healthy subjects.
| Original language | English |
|---|---|
| Pages (from-to) | 30-40 |
| Number of pages | 11 |
| Journal | Journal of Sport Rehabilitation |
| Volume | 19 |
| Issue number | 1 |
| State | Published - Feb 2010 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Orthopedics and Sports Medicine
- Rehabilitation
- Physical Therapy, Sports Therapy and Rehabilitation
- Biophysics
Cite this
Effects of menthol-based counterirritant on quadriceps motoneuron-pool excitability. / Huffman, Daniel H.; Pietrosimone, Brian G.; Grindstaff, Terry L.; Hart, Joseph M.; Saliba, Susan A.; Ingersoll, Christopher D.
In: Journal of Sport Rehabilitation, Vol. 19, No. 1, 02.2010, p. 30-40.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effects of menthol-based counterirritant on quadriceps motoneuron-pool excitability
AU - Huffman, Daniel H.
AU - Pietrosimone, Brian G.
AU - Grindstaff, Terry L.
AU - Hart, Joseph M.
AU - Saliba, Susan A.
AU - Ingersoll, Christopher D.
PY - 2010/2
Y1 - 2010/2
N2 - Context: Motoneuron-pool facilitation after cryotherapy may be mediated by stimulation of thermoreceptors surrounding a joint. It is unknown whether menthol counterirritants, which also stimulate thermoreceptors, have the same effect on motoneuron-pool excitability (MNPE). Objective: To compare quadriceps MNPE after a menthol-counterirritant application to the anterior knee, a sham counterirritant application, and a control treatment in healthy subjects. Design: A blinded, randomized controlled laboratory study. Setting: Laboratory. Participants: Thirty healthy subjects (16 m, 14 f; 24.1 ± 3.9 y, 170.6 ± 11.4 cm, 72.1 ± 15.6 kg) with no history of lower extremity surgery volunteered for this study. Intervention: Two milliliters of menthol or sham counterirritant was applied to the anterior knee; control subjects received no intervention. Main Outcome Measures: The average vastus medialis normalized Hoffmann reflex (Hmax:Mmax ratio) was used to measure MNPE. Measurements were recorded at 5, 15, 25, and 35 minutes postintervention and compared with baseline measures. Results: Hmax:Mmax ratios for all groups significantly decreased over time (F4,108 = 10.52, P <.001; menthol: baseline = .32 ± .20, 5 min = .29 ± .18, 15 min = .27 ± .18, 25 min = .28 ± .19, 35 min = .27 ± .18; sham: baseline = .46 ± .26, 5 min = .36 ± .20, 15 min = .35 ± .19, 25 min = .35 ± .20, 35 min = .34 ± .18; control: baseline = .48 ± .32, 5 min = .37 ± .27, 15 min = .37 ± .27, 25 min = .37 ± .29, 35 min = .35 ±.28). No significant Group × Time interaction or group differences in Hmax:Mmax were found. Conclusions: Menthol did not affect quadriceps MNPE in healthy subjects.
AB - Context: Motoneuron-pool facilitation after cryotherapy may be mediated by stimulation of thermoreceptors surrounding a joint. It is unknown whether menthol counterirritants, which also stimulate thermoreceptors, have the same effect on motoneuron-pool excitability (MNPE). Objective: To compare quadriceps MNPE after a menthol-counterirritant application to the anterior knee, a sham counterirritant application, and a control treatment in healthy subjects. Design: A blinded, randomized controlled laboratory study. Setting: Laboratory. Participants: Thirty healthy subjects (16 m, 14 f; 24.1 ± 3.9 y, 170.6 ± 11.4 cm, 72.1 ± 15.6 kg) with no history of lower extremity surgery volunteered for this study. Intervention: Two milliliters of menthol or sham counterirritant was applied to the anterior knee; control subjects received no intervention. Main Outcome Measures: The average vastus medialis normalized Hoffmann reflex (Hmax:Mmax ratio) was used to measure MNPE. Measurements were recorded at 5, 15, 25, and 35 minutes postintervention and compared with baseline measures. Results: Hmax:Mmax ratios for all groups significantly decreased over time (F4,108 = 10.52, P <.001; menthol: baseline = .32 ± .20, 5 min = .29 ± .18, 15 min = .27 ± .18, 25 min = .28 ± .19, 35 min = .27 ± .18; sham: baseline = .46 ± .26, 5 min = .36 ± .20, 15 min = .35 ± .19, 25 min = .35 ± .20, 35 min = .34 ± .18; control: baseline = .48 ± .32, 5 min = .37 ± .27, 15 min = .37 ± .27, 25 min = .37 ± .29, 35 min = .35 ±.28). No significant Group × Time interaction or group differences in Hmax:Mmax were found. Conclusions: Menthol did not affect quadriceps MNPE in healthy subjects.
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M3 - Article
C2 - 20231743
AN - SCOPUS:77951244992
VL - 19
SP - 30
EP - 40
JO - Journal of Sport Rehabilitation
JF - Journal of Sport Rehabilitation
SN - 1056-6716
IS - 1
ER -