Effects of moderate caffeine intake on the calcium economy of premenopausal women

M. Janet Barger-Lux, Robert P. Heaney, Mary Ruth Stegman

Research output: Contribution to journalArticle

63 Citations (Scopus)

Abstract

We examined directly the effects of a moderate dosage of caffeine (400 mg/d) on the calcium economy in 16 healthy premenopausal women in a double-blind, placebo-controlled crossover design. The subjects took divided doses of caffeine (100 mg/tablet) or identical-appearing placebos with decaffeinated coffee on personalized schedules for treatment periods lasting 19 d each and with 37-d interstudy intervals. We randomized the treatment sequence among subjects and studied them as inpatients under metabolic-balance conditions. We found no significant effects of caffeine on fractional calcium absorption, endogenous fecal calcium, or urine calcium, whether examined day by day or cumulatively. Although the mean balance shift was negative, the change was not significantly different from zero. There was evidence of altered bone remodeling, with slight decreases in bone accretion, bone resorption, and calcium pool turnover.

Original languageEnglish
Pages (from-to)722-725
Number of pages4
JournalAmerican Journal of Clinical Nutrition
Volume52
Issue number4
StatePublished - Oct 1990

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caffeine
Caffeine
Calcium
calcium
placebos
Placebos
bones
bone resorption
Bone Remodeling
Coffee
Bone Resorption
dosage
Cross-Over Studies
Tablets
Inpatients
Appointments and Schedules
urine
Urine
Bone and Bones
Therapeutics

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Food Science

Cite this

Effects of moderate caffeine intake on the calcium economy of premenopausal women. / Barger-Lux, M. Janet; Heaney, Robert P.; Stegman, Mary Ruth.

In: American Journal of Clinical Nutrition, Vol. 52, No. 4, 10.1990, p. 722-725.

Research output: Contribution to journalArticle

Barger-Lux, MJ, Heaney, RP & Stegman, MR 1990, 'Effects of moderate caffeine intake on the calcium economy of premenopausal women', American Journal of Clinical Nutrition, vol. 52, no. 4, pp. 722-725.
Barger-Lux, M. Janet ; Heaney, Robert P. ; Stegman, Mary Ruth. / Effects of moderate caffeine intake on the calcium economy of premenopausal women. In: American Journal of Clinical Nutrition. 1990 ; Vol. 52, No. 4. pp. 722-725.
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