In the present investigation, the effects of the MAO inhibitors, iproniazid, pargyline and tranylcypromine, as well as d-amphetamine or phencyclidine induced stereotyped behavior in rats has been evaluated. We have previously reported that phencyclidine produces a very characteristic stereotyped behavioral syndrome in rats. The possibility of a pharmacokinetic interaction between these compounds was evaluated by measuring the brain levels of phencyclidine and its metabolites in the various pretreatment groups.
|Original language||English (US)|
|Number of pages||3|
|Journal||Proceedings of the Western Pharmacology Society|
|State||Published - Jan 1 1979|
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