Abstract
In the present investigation, the effects of the MAO inhibitors, iproniazid, pargyline and tranylcypromine, as well as d-amphetamine or phencyclidine induced stereotyped behavior in rats has been evaluated. We have previously reported that phencyclidine produces a very characteristic stereotyped behavioral syndrome in rats. The possibility of a pharmacokinetic interaction between these compounds was evaluated by measuring the brain levels of phencyclidine and its metabolites in the various pretreatment groups.
| Original language | English |
|---|---|
| Pages (from-to) | 145-147 |
| Number of pages | 3 |
| Journal | Proceedings of the Western Pharmacology Society |
| Volume | VOL. 22 |
| State | Published - 1979 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Pharmacology
Cite this
Effects of monoamine oxidase inhibitors on phencyclidine induced stereotyped behavior and brain levels in rats. / Murray, Thomas F.; Horita, A.
In: Proceedings of the Western Pharmacology Society, Vol. VOL. 22, 1979, p. 145-147.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effects of monoamine oxidase inhibitors on phencyclidine induced stereotyped behavior and brain levels in rats
AU - Murray, Thomas F.
AU - Horita, A.
PY - 1979
Y1 - 1979
N2 - In the present investigation, the effects of the MAO inhibitors, iproniazid, pargyline and tranylcypromine, as well as d-amphetamine or phencyclidine induced stereotyped behavior in rats has been evaluated. We have previously reported that phencyclidine produces a very characteristic stereotyped behavioral syndrome in rats. The possibility of a pharmacokinetic interaction between these compounds was evaluated by measuring the brain levels of phencyclidine and its metabolites in the various pretreatment groups.
AB - In the present investigation, the effects of the MAO inhibitors, iproniazid, pargyline and tranylcypromine, as well as d-amphetamine or phencyclidine induced stereotyped behavior in rats has been evaluated. We have previously reported that phencyclidine produces a very characteristic stereotyped behavioral syndrome in rats. The possibility of a pharmacokinetic interaction between these compounds was evaluated by measuring the brain levels of phencyclidine and its metabolites in the various pretreatment groups.
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UR - http://www.scopus.com/inward/citedby.url?scp=0018557178&partnerID=8YFLogxK
M3 - Article
VL - VOL. 22
SP - 145
EP - 147
JO - Proceedings of the Western Pharmacology Society
JF - Proceedings of the Western Pharmacology Society
SN - 0083-8969
ER -