Effects of platelet activating factor on cyclic AMP accumulation in human lymphocytes

S. Wang, R. G. Townley

Research output: Contribution to journalArticle


The in vitro effects of platelet activating factor (PAF) on intracellular adenosine 3',5'-cyclic adenosine monophosphate (cAMP) accumulation were assessed in human lymphocytes in ten healthy volunteers and in eight asthmatic patients. Platelet activating factor to increased intracellular cAMP in both groups. In addition, PAF also enhanced the effects of isoproterenol and theophylline on intracellular cAMP production in these two groups.

Original languageEnglish
Pages (from-to)140-142
Number of pages3
JournalAnnals of Allergy
Issue number2
Publication statusPublished - 1992


All Science Journal Classification (ASJC) codes

  • Immunology and Allergy

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