Abstract
Context: Serum 25-hydroxyvitamin D (25OHD) is lower in women with darker skin color. Is it due to lower skin production, lower absorption, or different metabolism of vitamin D? Objectives: The objective of the study was to measure the effect of vitamin D3 on serum 25OHD and serum PTH in older African American women with vitamin D insufficiency and the serum 25OHD 20 ng/mL or less (50 nmol/L) in 97.5% of the African American women just as it did in the Caucasian women, and therefore, the RDA is the same for both groups. Because absorption and metabolism of oral vitamin D absorption is similar in both groups, lower levels of serum 25OHD in African Americans must be due to lower production of vitamin D in skin.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1137-1146 |
| Number of pages | 10 |
| Journal | Journal of Clinical Endocrinology and Metabolism |
| Volume | 98 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 1 2013 |
All Science Journal Classification (ASJC) codes
- Endocrinology, Diabetes and Metabolism
- Biochemistry
- Endocrinology
- Clinical Biochemistry
- Biochemistry, medical
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Gallagher, J. C., Peacock, M., Yalamanchili, V., & Smith, L. M. (2013). Effects of vitamin D supplementation in older African American women. Journal of Clinical Endocrinology and Metabolism, 98(3), 1137-1146. https://doi.org/10.1210/jc.2012-3106