Abstract
Context: Serum 25-hydroxyvitamin D (25OHD) is lower in women with darker skin color. Is it due to lower skin production, lower absorption, or different metabolism of vitamin D? Objectives: The objective of the study was to measure the effect of vitamin D3 on serum 25OHD and serum PTH in older African American women with vitamin D insufficiency and the serum 25OHD 20 ng/mL or less (50 nmol/L) in 97.5% of the African American women just as it did in the Caucasian women, and therefore, the RDA is the same for both groups. Because absorption and metabolism of oral vitamin D absorption is similar in both groups, lower levels of serum 25OHD in African Americans must be due to lower production of vitamin D in skin.
| Original language | English |
|---|---|
| Pages (from-to) | 1137-1146 |
| Number of pages | 10 |
| Journal | Journal of Clinical Endocrinology and Metabolism |
| Volume | 98 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 2013 |
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All Science Journal Classification (ASJC) codes
- Biochemistry
- Clinical Biochemistry
- Endocrinology
- Biochemistry, medical
- Endocrinology, Diabetes and Metabolism
Cite this
Effects of vitamin D supplementation in older African American women. / Gallagher, John Christopher G.; Peacock, Munro; Yalamanchili, Vinod; Smith, Lynette M.
In: Journal of Clinical Endocrinology and Metabolism, Vol. 98, No. 3, 03.2013, p. 1137-1146.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effects of vitamin D supplementation in older African American women
AU - Gallagher, John Christopher G.
AU - Peacock, Munro
AU - Yalamanchili, Vinod
AU - Smith, Lynette M.
PY - 2013/3
Y1 - 2013/3
N2 - Context: Serum 25-hydroxyvitamin D (25OHD) is lower in women with darker skin color. Is it due to lower skin production, lower absorption, or different metabolism of vitamin D? Objectives: The objective of the study was to measure the effect of vitamin D3 on serum 25OHD and serum PTH in older African American women with vitamin D insufficiency and the serum 25OHD 20 ng/mL or less (50 nmol/L) in 97.5% of the African American women just as it did in the Caucasian women, and therefore, the RDA is the same for both groups. Because absorption and metabolism of oral vitamin D absorption is similar in both groups, lower levels of serum 25OHD in African Americans must be due to lower production of vitamin D in skin.
AB - Context: Serum 25-hydroxyvitamin D (25OHD) is lower in women with darker skin color. Is it due to lower skin production, lower absorption, or different metabolism of vitamin D? Objectives: The objective of the study was to measure the effect of vitamin D3 on serum 25OHD and serum PTH in older African American women with vitamin D insufficiency and the serum 25OHD 20 ng/mL or less (50 nmol/L) in 97.5% of the African American women just as it did in the Caucasian women, and therefore, the RDA is the same for both groups. Because absorption and metabolism of oral vitamin D absorption is similar in both groups, lower levels of serum 25OHD in African Americans must be due to lower production of vitamin D in skin.
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U2 - 10.1210/jc.2012-3106
DO - 10.1210/jc.2012-3106
M3 - Article
C2 - 23386641
AN - SCOPUS:84874902705
VL - 98
SP - 1137
EP - 1146
JO - Journal of Clinical Endocrinology and Metabolism
JF - Journal of Clinical Endocrinology and Metabolism
SN - 0021-972X
IS - 3
ER -