@article{f321ffe6a19047b0a181b24f5500f6b4,
title = "Electrogenerated Chemiluminescent Detection of Polyamines on a Microfluidic Device Using Micromolded Carbon Paste Microelectrodes",
abstract = "A simple, sensitive, and rapid electrochemiluminescent (ECL) method was developed for the detection of several polyamines on a microfluidic chip. Rapid prototyping of poly(dimethylsiloxane) was used to fabricate flow channels and carbon paste microelectrodes. These devices are easily fabricated and amenable to ECL detection due to their planar and optically transparent nature. The ECL reaction between tris(2,2′-bipyridyl)ruthenium(II) and amine-containing co-reactants was used to generate the ECL signal. Experimental parameters were optimized and low micromolar limits of detection (S/N=3) were determined for four different polyamines. The method was successfully used to determine the concentration of spermine in milk samples.",
author = "Gross, {Erin M.} and Lowry, {Emily R.} and Schaffer, {Leah V.} and Henry, {Charles S.}",
note = "Funding Information: This publication was made possible by grants from the National Institute for General Medical Science (NIGMS) (5P20GM103427), a component of the National Institutes of Health (NIH), and its contents are the sole responsibility of the authors and do not necessarily represent the official views of NIGMS or NIH. The authors would also like to acknowledge funding from the Creighton University Ferlic Summer Research Scholarship, and the Clare Boothe Luce Foundation. The authors would also like to thank Rachel M. Feeny, John B. Wydallis, and Meghan M. Mensack for providing the molds for fabricating microfluidic devices and electrodes. We would also like to thank the Creighton Chemistry and Biochemistry Department and the College of Arts and Sciences. Publisher Copyright: {\textcopyright} 2022 Wiley-VCH GmbH.",
year = "2022",
doi = "10.1002/elan.202100410",
language = "English (US)",
journal = "Electroanalysis",
issn = "1040-0397",
publisher = "Wiley-VCH Verlag",
}