Abstract
We previously reported a significant decrease in neutrophils at 5 min and an increased number of neutrophils at 15 min after PAF-acether inhalation. To investigate the mechanism, we measured the neutrophil chemotactic activity of the sera. Neutrophil chemotactic activity (NCA) of the serum at 5 min was greater than at baseline (p <0.01) or at 15 min (p <0.05). Furthermore, we investigated the correlation between the change in NCA and decreased number of neutrophils. A significant correlation was found between these two at 5 min (r = 0.751, p <0.05). These data suggest that an elevation of NCA may play an important role in the decrease of circulating neutrophils after PAF-acether inhalation.
| Original language | English |
|---|---|
| Pages (from-to) | 199-202 |
| Number of pages | 4 |
| Journal | International Archives of Allergy and Applied Immunology |
| Volume | 92 |
| Issue number | 2 |
| State | Published - 1990 |
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All Science Journal Classification (ASJC) codes
- Immunology and Allergy
Cite this
Elevation of neutrophil chemotactic activity in the human serum and the decreased number of neutrophils after platelet-activating factor inhalation. / Miyagawa, H.; Nabe, M.; Hopp, R. J.; Agrawal, Devendra K.; Bewtra, Againdra K.; Townley, R. G.
In: International Archives of Allergy and Applied Immunology, Vol. 92, No. 2, 1990, p. 199-202.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Elevation of neutrophil chemotactic activity in the human serum and the decreased number of neutrophils after platelet-activating factor inhalation
AU - Miyagawa, H.
AU - Nabe, M.
AU - Hopp, R. J.
AU - Agrawal, Devendra K.
AU - Bewtra, Againdra K.
AU - Townley, R. G.
PY - 1990
Y1 - 1990
N2 - We previously reported a significant decrease in neutrophils at 5 min and an increased number of neutrophils at 15 min after PAF-acether inhalation. To investigate the mechanism, we measured the neutrophil chemotactic activity of the sera. Neutrophil chemotactic activity (NCA) of the serum at 5 min was greater than at baseline (p <0.01) or at 15 min (p <0.05). Furthermore, we investigated the correlation between the change in NCA and decreased number of neutrophils. A significant correlation was found between these two at 5 min (r = 0.751, p <0.05). These data suggest that an elevation of NCA may play an important role in the decrease of circulating neutrophils after PAF-acether inhalation.
AB - We previously reported a significant decrease in neutrophils at 5 min and an increased number of neutrophils at 15 min after PAF-acether inhalation. To investigate the mechanism, we measured the neutrophil chemotactic activity of the sera. Neutrophil chemotactic activity (NCA) of the serum at 5 min was greater than at baseline (p <0.01) or at 15 min (p <0.05). Furthermore, we investigated the correlation between the change in NCA and decreased number of neutrophils. A significant correlation was found between these two at 5 min (r = 0.751, p <0.05). These data suggest that an elevation of NCA may play an important role in the decrease of circulating neutrophils after PAF-acether inhalation.
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M3 - Article
VL - 92
SP - 199
EP - 202
JO - International Archives of Allergy and Immunology
JF - International Archives of Allergy and Immunology
SN - 1018-2438
IS - 2
ER -