Enantiocontrolled synthesis of (S)-3-substituted cycloalkanones from (s)-2-(p-tolylsulfinyl)-2-cycloalkenones and diorganomagnesium reagents.

Gary H. Posner, Martin Hulce

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

By appropriate choice of reaction conditions, the same enantiomerically pure (S)-(+)-2-(p-tolylsulfinyl)cycloalkenone can be converted into either an (R)-or an (S)-3-substituted cycloalkanone in good to excellent enantiomeric purity.

Original languageEnglish
Pages (from-to)379-382
Number of pages4
JournalTetrahedron Letters
Volume25
Issue number4
DOIs
StatePublished - 1984
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

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title = "Enantiocontrolled synthesis of (S)-3-substituted cycloalkanones from (s)-2-(p-tolylsulfinyl)-2-cycloalkenones and diorganomagnesium reagents.",
abstract = "By appropriate choice of reaction conditions, the same enantiomerically pure (S)-(+)-2-(p-tolylsulfinyl)cycloalkenone can be converted into either an (R)-or an (S)-3-substituted cycloalkanone in good to excellent enantiomeric purity.",
author = "Posner, {Gary H.} and Martin Hulce",
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AU - Posner, Gary H.

AU - Hulce, Martin

PY - 1984

Y1 - 1984

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AB - By appropriate choice of reaction conditions, the same enantiomerically pure (S)-(+)-2-(p-tolylsulfinyl)cycloalkenone can be converted into either an (R)-or an (S)-3-substituted cycloalkanone in good to excellent enantiomeric purity.

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DO - 10.1016/S0040-4039(00)99888-5

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