Endobronchial ultrasound-guided transbronchial needle aspiration: Determinants of sampling adequacy

Zachary S. DePew, Eric S. Edell, David E. Midthun, John J. Mullon, Aaron O. Bungum, Paul A. Decker, Fabien Maldonado

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Background: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is increasingly used to sample mediastinal and hilar lymph nodes and has excellent diagnostic test characteristics. The determinants of sampling adequacy, however, have not been extensively examined. We set out to determine which procedural variables were associated with acquisition of tissue sufficient for pathologic analysis during EBUS-TBNA. Methods: A retrospective analysis of all EBUS-TBNA cases performed over 32 months by 10 proceduralists at our institution was completed. Variables potentially associated with sampling adequacy were analyzed. Results: A total of 1304 procedures performed by 10 proceduralists while the patient received conscious sedation were included for analysis. Sampling adequacy was 94.2% overall and varied with the primary proceduralist (87% to 99.2%; P

Original languageEnglish (US)
Pages (from-to)271-276
Number of pages6
JournalJournal of Bronchology and Interventional Pulmonology
Issue number4
StatePublished - Oct 2012
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine


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