Abstract
Endogenous insulin secretion was quantified in patients with maturity-onset diabetes (MOD) whose diabetes was controllable solely by caloric regulation as primary therapy. Insulin was used adjunctively only and persistent attempts were made to withdraw it as weight loss occurred in response to diet. Insulin secretory capacity was measured by C-peptide response during a standard 100-g oral glucose tolerance test in 24 patients who achieved normalization of plasma glucose level as a result of dietary therapy alone. Summed C-peptide levels for the dietcontrolled diabetic patients was 7.8 ± 0.7 pmole/mL as compared with 6.1 ± 0.45 pmole/mL for a group of ten normalweight, nondiabetic volunteers.
| Original language | English |
|---|---|
| Pages (from-to) | 1617-1622 |
| Number of pages | 6 |
| Journal | Archives of Internal Medicine |
| Volume | 141 |
| Issue number | 12 |
| DOIs | |
| State | Published - 1981 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Internal Medicine
Cite this
Endogenous Insulin Secretion Measured by C-peptide in Maturity-Onset Diabetes Controllable by Diet Alone. / Rendell, Marc; Ross, David A.; Drew, Helen Mikesell; Zarriello, Joan.
In: Archives of Internal Medicine, Vol. 141, No. 12, 1981, p. 1617-1622.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Endogenous Insulin Secretion Measured by C-peptide in Maturity-Onset Diabetes Controllable by Diet Alone
AU - Rendell, Marc
AU - Ross, David A.
AU - Drew, Helen Mikesell
AU - Zarriello, Joan
PY - 1981
Y1 - 1981
N2 - Endogenous insulin secretion was quantified in patients with maturity-onset diabetes (MOD) whose diabetes was controllable solely by caloric regulation as primary therapy. Insulin was used adjunctively only and persistent attempts were made to withdraw it as weight loss occurred in response to diet. Insulin secretory capacity was measured by C-peptide response during a standard 100-g oral glucose tolerance test in 24 patients who achieved normalization of plasma glucose level as a result of dietary therapy alone. Summed C-peptide levels for the dietcontrolled diabetic patients was 7.8 ± 0.7 pmole/mL as compared with 6.1 ± 0.45 pmole/mL for a group of ten normalweight, nondiabetic volunteers.
AB - Endogenous insulin secretion was quantified in patients with maturity-onset diabetes (MOD) whose diabetes was controllable solely by caloric regulation as primary therapy. Insulin was used adjunctively only and persistent attempts were made to withdraw it as weight loss occurred in response to diet. Insulin secretory capacity was measured by C-peptide response during a standard 100-g oral glucose tolerance test in 24 patients who achieved normalization of plasma glucose level as a result of dietary therapy alone. Summed C-peptide levels for the dietcontrolled diabetic patients was 7.8 ± 0.7 pmole/mL as compared with 6.1 ± 0.45 pmole/mL for a group of ten normalweight, nondiabetic volunteers.
UR - http://www.scopus.com/inward/record.url?scp=0019788580&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0019788580&partnerID=8YFLogxK
U2 - 10.1001/archinte.1981.00340130061015
DO - 10.1001/archinte.1981.00340130061015
M3 - Article
C2 - 7030247
AN - SCOPUS:0019788580
VL - 141
SP - 1617
EP - 1622
JO - JAMA Internal Medicine
JF - JAMA Internal Medicine
SN - 2168-6106
IS - 12
ER -