Endometrial and ovarian cancer risk-reducing surgery in women with lynch syndrome

Kathleen M. Schmeler; Henry T. Lynch

Endometrial and ovarian cancer risk-reducing surgery in women with lynch syndrome

Kathleen M. Schmeler, Henry T. Lynch

Department of Preventive Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Lynch syndrome, aged 35 years or older, who have completed child-bearing. l If a woman with Lynch syndrome is undergoing surgery for colorectal carcinoma, consideration should be made for the concurrent performance of a hysterectomy and bilateral salpingo-oophorectomy. l Women with Lynch syndrome undergoing prophylactic hysterectomy may have an occult malignancy; therefore, preoperative endometrial biopsy and CA-125 should be considered. l Patients undergoing prophylactic hysterectomy for Lynch syndrome should have an intraoperative evaluation of the uterus and ovaries.

Original language	English (US)
Title of host publication	Hereditary Gynecologic Cancer
Subtitle of host publication	Risk, Prevention and Management
Publisher	CRC Press
Pages	185-193
Number of pages	9
ISBN (Electronic)	9781420052886
ISBN (Print)	142005287X, 9781420052879
State	Published - Jan 1 2008

All Science Journal Classification (ASJC) codes

Medicine(all)
Biochemistry, Genetics and Molecular Biology(all)

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abstract = "Lynch syndrome, aged 35 years or older, who have completed child-bearing. l If a woman with Lynch syndrome is undergoing surgery for colorectal carcinoma, consideration should be made for the concurrent performance of a hysterectomy and bilateral salpingo-oophorectomy. l Women with Lynch syndrome undergoing prophylactic hysterectomy may have an occult malignancy; therefore, preoperative endometrial biopsy and CA-125 should be considered. l Patients undergoing prophylactic hysterectomy for Lynch syndrome should have an intraoperative evaluation of the uterus and ovaries.",

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N2 - Lynch syndrome, aged 35 years or older, who have completed child-bearing. l If a woman with Lynch syndrome is undergoing surgery for colorectal carcinoma, consideration should be made for the concurrent performance of a hysterectomy and bilateral salpingo-oophorectomy. l Women with Lynch syndrome undergoing prophylactic hysterectomy may have an occult malignancy; therefore, preoperative endometrial biopsy and CA-125 should be considered. l Patients undergoing prophylactic hysterectomy for Lynch syndrome should have an intraoperative evaluation of the uterus and ovaries.

AB - Lynch syndrome, aged 35 years or older, who have completed child-bearing. l If a woman with Lynch syndrome is undergoing surgery for colorectal carcinoma, consideration should be made for the concurrent performance of a hysterectomy and bilateral salpingo-oophorectomy. l Women with Lynch syndrome undergoing prophylactic hysterectomy may have an occult malignancy; therefore, preoperative endometrial biopsy and CA-125 should be considered. l Patients undergoing prophylactic hysterectomy for Lynch syndrome should have an intraoperative evaluation of the uterus and ovaries.

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