Eruptive xanthomas and chest pain in the absence of coronary artery disease

Patricia P. Hentges, Christopher Huerter

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Because hyperlipidemia may present as xanthomas, a dermatologist may be the first to diagnose these skin lesions and associated lipid abnormalities. 1 Xanthomas are of concern because of their association with coronary artery disease and pancreatitis. We describe the case of a 40-year-old white male with chest pain and eruptive xanthomas. Laboratory tests revealed severe hypercholesterolemia, hypertriglyceridemia, and diabetes mellitus, and the histopathology of the skin lesions was consistent with eruptive xanthomas. Surprisingly, even with overwhelming risk factors for both atherosclerosis and pancreatitis, this patient did not show evidence of either disease process. After initiating therapy for the diabetes and hyperlipidemia, the patient has had no recurrence of chest pain, and the skin lesions have gradually resolved. The most likely explanation for this patient's pattern of symptoms and laboratory results is the chylomicronemia syndrome, which can be seen in patients with type I or type V hyperlipoproteinemia.

Original languageEnglish
Pages (from-to)299-302
Number of pages4
JournalCutis
Volume67
Issue number4
StatePublished - 2001

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Xanthomatosis
Chest Pain
Coronary Artery Disease
Hyperlipidemias
Pancreatitis
Skin
Hyperlipoproteinemia Type V
Hypertriglyceridemia
Hypercholesterolemia
Atherosclerosis
Diabetes Mellitus
Lipids
Recurrence

All Science Journal Classification (ASJC) codes

  • Dermatology
  • Immunology and Allergy

Cite this

Eruptive xanthomas and chest pain in the absence of coronary artery disease. / Hentges, Patricia P.; Huerter, Christopher.

In: Cutis, Vol. 67, No. 4, 2001, p. 299-302.

Research output: Contribution to journalArticle

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