Estimates of optimal vitamin D status

Bess Dawson-Hughes, Robert P. Heaney, Michael F. Holick, Paul Lips, Pierre J. Meunier, Reinhold Vieth

Research output: Contribution to journalReview article

1354 Citations (Scopus)

Abstract

Vitamin D has captured attention as an important determinant of bone health, but there is no common definition of optimal vitamin D status. Herein, we address the question: What is the optimal circulating level of 25-hydroxyvitamin D [25(OH)D] for the skeleton? The opinions of the authors on the minimum level of serum 25(OH)D that is optimal for fracture prevention varied between 50 and 80 nmol/l. However, for five of the six authors, the minimum desirable 25(OH)D concentration clusters between 70 and 80 nmol/l. The authors recognize that the average older man and woman will need intakes of at least 20 to 25 mcg (800 to 1,000 IU) per day of vitamin D3 to reach a serum 25(OH)D level of 75 nmol/l. Based on the available evidence, we believe that if older men and women maintain serum levels of 25(OH)D that are higher than the consensus median threshold of 75 nmol/l, they will be at lower risk of fracture.

Original languageEnglish
Pages (from-to)713-716
Number of pages4
JournalOsteoporosis International
Volume16
Issue number7
DOIs
StatePublished - Jul 2005

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Vitamin D
Serum
Cholecalciferol
Skeleton
Bone and Bones
Health
25-hydroxyvitamin D

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Dawson-Hughes, B., Heaney, R. P., Holick, M. F., Lips, P., Meunier, P. J., & Vieth, R. (2005). Estimates of optimal vitamin D status. Osteoporosis International, 16(7), 713-716. https://doi.org/10.1007/s00198-005-1867-7

Estimates of optimal vitamin D status. / Dawson-Hughes, Bess; Heaney, Robert P.; Holick, Michael F.; Lips, Paul; Meunier, Pierre J.; Vieth, Reinhold.

In: Osteoporosis International, Vol. 16, No. 7, 07.2005, p. 713-716.

Research output: Contribution to journalReview article

Dawson-Hughes, B, Heaney, RP, Holick, MF, Lips, P, Meunier, PJ & Vieth, R 2005, 'Estimates of optimal vitamin D status', Osteoporosis International, vol. 16, no. 7, pp. 713-716. https://doi.org/10.1007/s00198-005-1867-7
Dawson-Hughes B, Heaney RP, Holick MF, Lips P, Meunier PJ, Vieth R. Estimates of optimal vitamin D status. Osteoporosis International. 2005 Jul;16(7):713-716. https://doi.org/10.1007/s00198-005-1867-7
Dawson-Hughes, Bess ; Heaney, Robert P. ; Holick, Michael F. ; Lips, Paul ; Meunier, Pierre J. ; Vieth, Reinhold. / Estimates of optimal vitamin D status. In: Osteoporosis International. 2005 ; Vol. 16, No. 7. pp. 713-716.
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