Estrogens in the prevention of osteoporosis in postmenopausal women

H. K. Genant, D. J. Baylink, John Christopher G. Gallagher

Research output: Contribution to journalReview article

136 Citations (Scopus)

Abstract

Menopausal-related bone loss leaves a woman at high risk for fractures. Estrogen use by postmenopausal women, especially when started within 3 years of the last menstrual period, prevents bone loss and reduces the risk of osteoporotic fractures. Estrogens do not restore lost bone. Withdrawal of estrogen therapy is followed by significant bone loss, thus suggesting that long-term therapy is needed. Concomitant progesterone therapy does not impair estrogen's bone-preserving activity.

Original languageEnglish
Pages (from-to)1842-1846
Number of pages5
JournalAmerican Journal of Obstetrics and Gynecology
Volume161
Issue number6 II SUPPL.
StatePublished - 1989

Fingerprint

Postmenopausal Osteoporosis
Estrogens
Bone and Bones
Osteoporotic Fractures
Progesterone
Therapeutics

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Obstetrics and Gynecology

Cite this

Estrogens in the prevention of osteoporosis in postmenopausal women. / Genant, H. K.; Baylink, D. J.; Gallagher, John Christopher G.

In: American Journal of Obstetrics and Gynecology, Vol. 161, No. 6 II SUPPL., 1989, p. 1842-1846.

Research output: Contribution to journalReview article

@article{724c34053d0349a29d517e980cc19edb,
title = "Estrogens in the prevention of osteoporosis in postmenopausal women",
abstract = "Menopausal-related bone loss leaves a woman at high risk for fractures. Estrogen use by postmenopausal women, especially when started within 3 years of the last menstrual period, prevents bone loss and reduces the risk of osteoporotic fractures. Estrogens do not restore lost bone. Withdrawal of estrogen therapy is followed by significant bone loss, thus suggesting that long-term therapy is needed. Concomitant progesterone therapy does not impair estrogen's bone-preserving activity.",
author = "Genant, {H. K.} and Baylink, {D. J.} and Gallagher, {John Christopher G.}",
year = "1989",
language = "English",
volume = "161",
pages = "1842--1846",
journal = "American Journal of Obstetrics and Gynecology",
issn = "0002-9378",
publisher = "Mosby Inc.",
number = "6 II SUPPL.",

}

TY - JOUR

T1 - Estrogens in the prevention of osteoporosis in postmenopausal women

AU - Genant, H. K.

AU - Baylink, D. J.

AU - Gallagher, John Christopher G.

PY - 1989

Y1 - 1989

N2 - Menopausal-related bone loss leaves a woman at high risk for fractures. Estrogen use by postmenopausal women, especially when started within 3 years of the last menstrual period, prevents bone loss and reduces the risk of osteoporotic fractures. Estrogens do not restore lost bone. Withdrawal of estrogen therapy is followed by significant bone loss, thus suggesting that long-term therapy is needed. Concomitant progesterone therapy does not impair estrogen's bone-preserving activity.

AB - Menopausal-related bone loss leaves a woman at high risk for fractures. Estrogen use by postmenopausal women, especially when started within 3 years of the last menstrual period, prevents bone loss and reduces the risk of osteoporotic fractures. Estrogens do not restore lost bone. Withdrawal of estrogen therapy is followed by significant bone loss, thus suggesting that long-term therapy is needed. Concomitant progesterone therapy does not impair estrogen's bone-preserving activity.

UR - http://www.scopus.com/inward/record.url?scp=0024843527&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024843527&partnerID=8YFLogxK

M3 - Review article

VL - 161

SP - 1842

EP - 1846

JO - American Journal of Obstetrics and Gynecology

JF - American Journal of Obstetrics and Gynecology

SN - 0002-9378

IS - 6 II SUPPL.

ER -