Etiology of recurrent gastroesophageal reflux disease

Ziad T. Awad, Charles Filipi

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Gastroesophageal reflux disease (GERD) is a common disease that accounts for approximately 75 per cent of the pathology of the esophagus. Forty per cent of the adults in the USA have occasional heartburn, and ten per cent experience heartburn daily.1,2 It is estimated that 20 per cent of patients with GERD develop serious complications, such as ulceration, stricture, and Barrett’s metaplasia. Although medical therapy may be effective, it is often required for a protracted period of time. In addition, prolonged therapy often requires escalated dosages, and discontinuation of medications may result in an early recurrence of symptoms. Surgery has improved because of a better understanding of the underlying pathophysiology of GERD and technical refinements of operative techniques.3,4 A controlled, randomized trial showed superiority of surgical therapy for the treatment of severe GERD, with less frequent side effects than with non-surgical management.5

Original languageEnglish (US)
Title of host publicationLaparoscopic Hernia Surgery
Subtitle of host publicationAn Operative Guide
PublisherCRC Press
Pages218-225
Number of pages8
ISBN (Electronic)9781444113952
ISBN (Print)034080940X, 9780340809402
StatePublished - Jan 1 2002
Externally publishedYes

Fingerprint

Gastroesophageal Reflux
Heartburn
Barrett Esophagus
Therapeutics
Esophagus
Pathologic Constriction
Randomized Controlled Trials
Pathology
Recurrence

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Awad, Z. T., & Filipi, C. (2002). Etiology of recurrent gastroesophageal reflux disease. In Laparoscopic Hernia Surgery: An Operative Guide (pp. 218-225). CRC Press.

Etiology of recurrent gastroesophageal reflux disease. / Awad, Ziad T.; Filipi, Charles.

Laparoscopic Hernia Surgery: An Operative Guide. CRC Press, 2002. p. 218-225.

Research output: Chapter in Book/Report/Conference proceedingChapter

Awad, ZT & Filipi, C 2002, Etiology of recurrent gastroesophageal reflux disease. in Laparoscopic Hernia Surgery: An Operative Guide. CRC Press, pp. 218-225.
Awad ZT, Filipi C. Etiology of recurrent gastroesophageal reflux disease. In Laparoscopic Hernia Surgery: An Operative Guide. CRC Press. 2002. p. 218-225
Awad, Ziad T. ; Filipi, Charles. / Etiology of recurrent gastroesophageal reflux disease. Laparoscopic Hernia Surgery: An Operative Guide. CRC Press, 2002. pp. 218-225
@inbook{c89abc2ab5b4426699306b9a9b8681ae,
title = "Etiology of recurrent gastroesophageal reflux disease",
abstract = "Gastroesophageal reflux disease (GERD) is a common disease that accounts for approximately 75 per cent of the pathology of the esophagus. Forty per cent of the adults in the USA have occasional heartburn, and ten per cent experience heartburn daily.1,2 It is estimated that 20 per cent of patients with GERD develop serious complications, such as ulceration, stricture, and Barrett’s metaplasia. Although medical therapy may be effective, it is often required for a protracted period of time. In addition, prolonged therapy often requires escalated dosages, and discontinuation of medications may result in an early recurrence of symptoms. Surgery has improved because of a better understanding of the underlying pathophysiology of GERD and technical refinements of operative techniques.3,4 A controlled, randomized trial showed superiority of surgical therapy for the treatment of severe GERD, with less frequent side effects than with non-surgical management.5",
author = "Awad, {Ziad T.} and Charles Filipi",
year = "2002",
month = "1",
day = "1",
language = "English (US)",
isbn = "034080940X",
pages = "218--225",
booktitle = "Laparoscopic Hernia Surgery",
publisher = "CRC Press",

}

TY - CHAP

T1 - Etiology of recurrent gastroesophageal reflux disease

AU - Awad, Ziad T.

AU - Filipi, Charles

PY - 2002/1/1

Y1 - 2002/1/1

N2 - Gastroesophageal reflux disease (GERD) is a common disease that accounts for approximately 75 per cent of the pathology of the esophagus. Forty per cent of the adults in the USA have occasional heartburn, and ten per cent experience heartburn daily.1,2 It is estimated that 20 per cent of patients with GERD develop serious complications, such as ulceration, stricture, and Barrett’s metaplasia. Although medical therapy may be effective, it is often required for a protracted period of time. In addition, prolonged therapy often requires escalated dosages, and discontinuation of medications may result in an early recurrence of symptoms. Surgery has improved because of a better understanding of the underlying pathophysiology of GERD and technical refinements of operative techniques.3,4 A controlled, randomized trial showed superiority of surgical therapy for the treatment of severe GERD, with less frequent side effects than with non-surgical management.5

AB - Gastroesophageal reflux disease (GERD) is a common disease that accounts for approximately 75 per cent of the pathology of the esophagus. Forty per cent of the adults in the USA have occasional heartburn, and ten per cent experience heartburn daily.1,2 It is estimated that 20 per cent of patients with GERD develop serious complications, such as ulceration, stricture, and Barrett’s metaplasia. Although medical therapy may be effective, it is often required for a protracted period of time. In addition, prolonged therapy often requires escalated dosages, and discontinuation of medications may result in an early recurrence of symptoms. Surgery has improved because of a better understanding of the underlying pathophysiology of GERD and technical refinements of operative techniques.3,4 A controlled, randomized trial showed superiority of surgical therapy for the treatment of severe GERD, with less frequent side effects than with non-surgical management.5

UR - http://www.scopus.com/inward/record.url?scp=85057291349&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85057291349&partnerID=8YFLogxK

M3 - Chapter

SN - 034080940X

SN - 9780340809402

SP - 218

EP - 225

BT - Laparoscopic Hernia Surgery

PB - CRC Press

ER -