Abstract
Mammalian outer hair cells (OHCs) contain Ca and K channels in their synaptic pole. We questioned if the ontogeny of potassium currents of OHCs depends on the neural induction of early afferent contact. By recording whole-cell currents of OHCs grown in organotypic cultures deprived of afferent innervation, we show that a Ca-activated K channel is expressed in these cells, suggesting that the ontogeny of the K channel is an intrinsic process.
| Original language | English |
|---|---|
| Pages (from-to) | 95-97 |
| Number of pages | 3 |
| Journal | Developmental Brain Research |
| Volume | 103 |
| Issue number | 1 |
| DOIs | |
| State | Published - Oct 20 1997 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Developmental Biology
- Developmental Neuroscience
Cite this
Expression of potassium channels in gerbil outer hair cells during development does not require neural induction. / He, David Z.; Dallos, Peter.
In: Developmental Brain Research, Vol. 103, No. 1, 20.10.1997, p. 95-97.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Expression of potassium channels in gerbil outer hair cells during development does not require neural induction
AU - He, David Z.
AU - Dallos, Peter
PY - 1997/10/20
Y1 - 1997/10/20
N2 - Mammalian outer hair cells (OHCs) contain Ca and K channels in their synaptic pole. We questioned if the ontogeny of potassium currents of OHCs depends on the neural induction of early afferent contact. By recording whole-cell currents of OHCs grown in organotypic cultures deprived of afferent innervation, we show that a Ca-activated K channel is expressed in these cells, suggesting that the ontogeny of the K channel is an intrinsic process.
AB - Mammalian outer hair cells (OHCs) contain Ca and K channels in their synaptic pole. We questioned if the ontogeny of potassium currents of OHCs depends on the neural induction of early afferent contact. By recording whole-cell currents of OHCs grown in organotypic cultures deprived of afferent innervation, we show that a Ca-activated K channel is expressed in these cells, suggesting that the ontogeny of the K channel is an intrinsic process.
UR - http://www.scopus.com/inward/record.url?scp=0030691060&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030691060&partnerID=8YFLogxK
U2 - 10.1016/S0165-3806(97)00120-X
DO - 10.1016/S0165-3806(97)00120-X
M3 - Article
VL - 103
SP - 95
EP - 97
JO - Developmental Brain Research
JF - Developmental Brain Research
SN - 0165-3806
IS - 1
ER -