Failure of cefepime therapy in treatment of Klebsiella pneumoniae bacteremia

Wonkeun Song; Ellen S. Moland; Nancy D. Hanson; James S. Lewis; James H. Jorgensen; Kenneth S. Thomson

doi:10.1128/JCM.43.9.4891-4894.2005

Failure of cefepime therapy in treatment of Klebsiella pneumoniae bacteremia

Wonkeun Song, Ellen S. Moland, Nancy D. Hanson, James S. Lewis, James H. Jorgensen, Kenneth S. Thomson

Department of Medical Microbiology and Immunology

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

A case of failure of cefepime treatment of a bloodstream infection with AmpC-producing Klebsiella pneumoniae is reported. The failure was attributed to extended-spectrum β-lactamase (ESBL) acquisition by the isolate, possibly during therapy. Problems encountered with ESBL detection in AmpC-producing isolates are discussed.

Original language	English (US)
Pages (from-to)	4891-4894
Number of pages	4
Journal	Journal of clinical microbiology
Volume	43
Issue number	9
DOIs	https://doi.org/10.1128/JCM.43.9.4891-4894.2005
State	Published - Sep 2005

All Science Journal Classification (ASJC) codes

Microbiology (medical)

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abstract = "A case of failure of cefepime treatment of a bloodstream infection with AmpC-producing Klebsiella pneumoniae is reported. The failure was attributed to extended-spectrum β-lactamase (ESBL) acquisition by the isolate, possibly during therapy. Problems encountered with ESBL detection in AmpC-producing isolates are discussed.",

author = "Wonkeun Song and Moland, {Ellen S.} and Hanson, {Nancy D.} and Lewis, {James S.} and Jorgensen, {James H.} and Thomson, {Kenneth S.}",

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AU - Jorgensen, James H.

AU - Thomson, Kenneth S.

PY - 2005/9

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AB - A case of failure of cefepime treatment of a bloodstream infection with AmpC-producing Klebsiella pneumoniae is reported. The failure was attributed to extended-spectrum β-lactamase (ESBL) acquisition by the isolate, possibly during therapy. Problems encountered with ESBL detection in AmpC-producing isolates are discussed.

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Failure of cefepime therapy in treatment of Klebsiella pneumoniae bacteremia

Abstract

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