Failure of cefepime therapy in treatment of Klebsiella pneumoniae bacteremia

Wonkeun Song, Ellen S. Moland, Nancy D. Hanson, James S. Lewis, James H. Jorgensen, Kenneth S. Thomson

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

A case of failure of cefepime treatment of a bloodstream infection with AmpC-producing Klebsiella pneumoniae is reported. The failure was attributed to extended-spectrum β-lactamase (ESBL) acquisition by the isolate, possibly during therapy. Problems encountered with ESBL detection in AmpC-producing isolates are discussed.

Original languageEnglish
Pages (from-to)4891-4894
Number of pages4
JournalJournal of Clinical Microbiology
Volume43
Issue number9
DOIs
StatePublished - Sep 2005

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Klebsiella pneumoniae
Bacteremia
Treatment Failure
Infection
Therapeutics
cefepime

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Microbiology

Cite this

Failure of cefepime therapy in treatment of Klebsiella pneumoniae bacteremia. / Song, Wonkeun; Moland, Ellen S.; Hanson, Nancy D.; Lewis, James S.; Jorgensen, James H.; Thomson, Kenneth S.

In: Journal of Clinical Microbiology, Vol. 43, No. 9, 09.2005, p. 4891-4894.

Research output: Contribution to journalArticle

Song, Wonkeun ; Moland, Ellen S. ; Hanson, Nancy D. ; Lewis, James S. ; Jorgensen, James H. ; Thomson, Kenneth S. / Failure of cefepime therapy in treatment of Klebsiella pneumoniae bacteremia. In: Journal of Clinical Microbiology. 2005 ; Vol. 43, No. 9. pp. 4891-4894.
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