Failure of cefepime therapy in treatment of Klebsiella pneumoniae bacteremia

Wonkeun Song, Ellen S. Moland, Nancy D. Hanson, James S. Lewis, James H. Jorgensen, Kenneth S. Thomson

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A case of failure of cefepime treatment of a bloodstream infection with AmpC-producing Klebsiella pneumoniae is reported. The failure was attributed to extended-spectrum β-lactamase (ESBL) acquisition by the isolate, possibly during therapy. Problems encountered with ESBL detection in AmpC-producing isolates are discussed.

Original languageEnglish
Pages (from-to)4891-4894
Number of pages4
JournalJournal of Clinical Microbiology
Issue number9
Publication statusPublished - Sep 2005


All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Microbiology

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