Abstract
Carcinomas of the breast and ovary were observed in 3 generations of women in 2 families. These findings, coupled with observations from a normal population and from the literature, suggest a new familial cancer association, showing a proclivity to carcinoma of the breast and ovary. Such families could be used profitably for studies of carcinogenesis; in addition, attention should be given toward improving their lot through earlier diagnosis of cancer because of the known familial risk. Additional studies will be necessary to evaluate more fully the suspected familial association of carcinoma of the breat and ovary, it mode of transmission, and frequency in the population.
| Original language | English |
|---|---|
| Pages (from-to) | 717-724 |
| Number of pages | 8 |
| Journal | Surgery Gynecology and Obstetrics |
| Volume | 138 |
| Issue number | 5 |
| State | Published - 1974 |
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All Science Journal Classification (ASJC) codes
- Surgery
- Obstetrics and Gynecology
Cite this
Familial association of carcinoma of the breast and ovary. / Lynch, Henry T.; Guirgis, H. A.; Albert, S.; Brennan, M.; Lynch, J.; Kraft, C.; Pocekay, D.; Vaughns, C.; Kaplan, A.
In: Surgery Gynecology and Obstetrics, Vol. 138, No. 5, 1974, p. 717-724.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Familial association of carcinoma of the breast and ovary
AU - Lynch, Henry T.
AU - Guirgis, H. A.
AU - Albert, S.
AU - Brennan, M.
AU - Lynch, J.
AU - Kraft, C.
AU - Pocekay, D.
AU - Vaughns, C.
AU - Kaplan, A.
PY - 1974
Y1 - 1974
N2 - Carcinomas of the breast and ovary were observed in 3 generations of women in 2 families. These findings, coupled with observations from a normal population and from the literature, suggest a new familial cancer association, showing a proclivity to carcinoma of the breast and ovary. Such families could be used profitably for studies of carcinogenesis; in addition, attention should be given toward improving their lot through earlier diagnosis of cancer because of the known familial risk. Additional studies will be necessary to evaluate more fully the suspected familial association of carcinoma of the breat and ovary, it mode of transmission, and frequency in the population.
AB - Carcinomas of the breast and ovary were observed in 3 generations of women in 2 families. These findings, coupled with observations from a normal population and from the literature, suggest a new familial cancer association, showing a proclivity to carcinoma of the breast and ovary. Such families could be used profitably for studies of carcinogenesis; in addition, attention should be given toward improving their lot through earlier diagnosis of cancer because of the known familial risk. Additional studies will be necessary to evaluate more fully the suspected familial association of carcinoma of the breat and ovary, it mode of transmission, and frequency in the population.
UR - http://www.scopus.com/inward/record.url?scp=0016253104&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0016253104&partnerID=8YFLogxK
M3 - Article
VL - 138
SP - 717
EP - 724
JO - Journal of the American College of Surgeons
JF - Journal of the American College of Surgeons
SN - 1072-7515
IS - 5
ER -