Familial association of carcinoma of the breast and ovary

Henry T. Lynch, H. A. Guirgis, S. Albert, M. Brennan, J. Lynch, C. Kraft, D. Pocekay, C. Vaughns, A. Kaplan

Research output: Contribution to journalArticle

71 Citations (Scopus)

Abstract

Carcinomas of the breast and ovary were observed in 3 generations of women in 2 families. These findings, coupled with observations from a normal population and from the literature, suggest a new familial cancer association, showing a proclivity to carcinoma of the breast and ovary. Such families could be used profitably for studies of carcinogenesis; in addition, attention should be given toward improving their lot through earlier diagnosis of cancer because of the known familial risk. Additional studies will be necessary to evaluate more fully the suspected familial association of carcinoma of the breat and ovary, it mode of transmission, and frequency in the population.

Original languageEnglish
Pages (from-to)717-724
Number of pages8
JournalSurgery Gynecology and Obstetrics
Volume138
Issue number5
StatePublished - 1974

Fingerprint

Ovary
Breast Neoplasms
Early Detection of Cancer
Population
Carcinogenesis
Carcinoma
Neoplasms

All Science Journal Classification (ASJC) codes

  • Surgery
  • Obstetrics and Gynecology

Cite this

Lynch, H. T., Guirgis, H. A., Albert, S., Brennan, M., Lynch, J., Kraft, C., ... Kaplan, A. (1974). Familial association of carcinoma of the breast and ovary. Surgery Gynecology and Obstetrics, 138(5), 717-724.

Familial association of carcinoma of the breast and ovary. / Lynch, Henry T.; Guirgis, H. A.; Albert, S.; Brennan, M.; Lynch, J.; Kraft, C.; Pocekay, D.; Vaughns, C.; Kaplan, A.

In: Surgery Gynecology and Obstetrics, Vol. 138, No. 5, 1974, p. 717-724.

Research output: Contribution to journalArticle

Lynch, HT, Guirgis, HA, Albert, S, Brennan, M, Lynch, J, Kraft, C, Pocekay, D, Vaughns, C & Kaplan, A 1974, 'Familial association of carcinoma of the breast and ovary', Surgery Gynecology and Obstetrics, vol. 138, no. 5, pp. 717-724.
Lynch HT, Guirgis HA, Albert S, Brennan M, Lynch J, Kraft C et al. Familial association of carcinoma of the breast and ovary. Surgery Gynecology and Obstetrics. 1974;138(5):717-724.
Lynch, Henry T. ; Guirgis, H. A. ; Albert, S. ; Brennan, M. ; Lynch, J. ; Kraft, C. ; Pocekay, D. ; Vaughns, C. ; Kaplan, A. / Familial association of carcinoma of the breast and ovary. In: Surgery Gynecology and Obstetrics. 1974 ; Vol. 138, No. 5. pp. 717-724.
@article{059fbdda845a4f07818e5822eca849d2,
title = "Familial association of carcinoma of the breast and ovary",
abstract = "Carcinomas of the breast and ovary were observed in 3 generations of women in 2 families. These findings, coupled with observations from a normal population and from the literature, suggest a new familial cancer association, showing a proclivity to carcinoma of the breast and ovary. Such families could be used profitably for studies of carcinogenesis; in addition, attention should be given toward improving their lot through earlier diagnosis of cancer because of the known familial risk. Additional studies will be necessary to evaluate more fully the suspected familial association of carcinoma of the breat and ovary, it mode of transmission, and frequency in the population.",
author = "Lynch, {Henry T.} and Guirgis, {H. A.} and S. Albert and M. Brennan and J. Lynch and C. Kraft and D. Pocekay and C. Vaughns and A. Kaplan",
year = "1974",
language = "English",
volume = "138",
pages = "717--724",
journal = "Journal of the American College of Surgeons",
issn = "1072-7515",
publisher = "Elsevier Inc.",
number = "5",

}

TY - JOUR

T1 - Familial association of carcinoma of the breast and ovary

AU - Lynch, Henry T.

AU - Guirgis, H. A.

AU - Albert, S.

AU - Brennan, M.

AU - Lynch, J.

AU - Kraft, C.

AU - Pocekay, D.

AU - Vaughns, C.

AU - Kaplan, A.

PY - 1974

Y1 - 1974

N2 - Carcinomas of the breast and ovary were observed in 3 generations of women in 2 families. These findings, coupled with observations from a normal population and from the literature, suggest a new familial cancer association, showing a proclivity to carcinoma of the breast and ovary. Such families could be used profitably for studies of carcinogenesis; in addition, attention should be given toward improving their lot through earlier diagnosis of cancer because of the known familial risk. Additional studies will be necessary to evaluate more fully the suspected familial association of carcinoma of the breat and ovary, it mode of transmission, and frequency in the population.

AB - Carcinomas of the breast and ovary were observed in 3 generations of women in 2 families. These findings, coupled with observations from a normal population and from the literature, suggest a new familial cancer association, showing a proclivity to carcinoma of the breast and ovary. Such families could be used profitably for studies of carcinogenesis; in addition, attention should be given toward improving their lot through earlier diagnosis of cancer because of the known familial risk. Additional studies will be necessary to evaluate more fully the suspected familial association of carcinoma of the breat and ovary, it mode of transmission, and frequency in the population.

UR - http://www.scopus.com/inward/record.url?scp=0016253104&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0016253104&partnerID=8YFLogxK

M3 - Article

VL - 138

SP - 717

EP - 724

JO - Journal of the American College of Surgeons

JF - Journal of the American College of Surgeons

SN - 1072-7515

IS - 5

ER -