Familial atypical multiple mole-melanoma syndrome

Henry T. Lynch, B. C. Frichot, J. F. Lynch

Research output: Contribution to journalArticle

242 Citations (Scopus)

Abstract

A family is described showing concordance for malignant melanoma and a cutaneous phenotype characterised by multiple large moles of variable size and colour (reddish-brown to bright red) with pigmentary leakage. Transmission of the cutaneous phenotype in the subject family, and in several others currently under investigation, shows an inheritance pattern consistent with a simple autosomal dominant factor. This cutaneous phenotype signifying melanoma risk may now be added to an increasing body of knowledge dealing with cancer-related genodermatoses.

Original languageEnglish
Pages (from-to)352-356
Number of pages5
JournalJournal of Medical Genetics
Volume15
Issue number5
StatePublished - 1978

Fingerprint

Dysplastic Nevus Syndrome
Phenotype
Inheritance Patterns
Skin
Melanoma
Color
Neoplasms

All Science Journal Classification (ASJC) codes

  • Genetics
  • Genetics(clinical)

Cite this

Lynch, H. T., Frichot, B. C., & Lynch, J. F. (1978). Familial atypical multiple mole-melanoma syndrome. Journal of Medical Genetics, 15(5), 352-356.

Familial atypical multiple mole-melanoma syndrome. / Lynch, Henry T.; Frichot, B. C.; Lynch, J. F.

In: Journal of Medical Genetics, Vol. 15, No. 5, 1978, p. 352-356.

Research output: Contribution to journalArticle

Lynch, HT, Frichot, BC & Lynch, JF 1978, 'Familial atypical multiple mole-melanoma syndrome', Journal of Medical Genetics, vol. 15, no. 5, pp. 352-356.
Lynch, Henry T. ; Frichot, B. C. ; Lynch, J. F. / Familial atypical multiple mole-melanoma syndrome. In: Journal of Medical Genetics. 1978 ; Vol. 15, No. 5. pp. 352-356.
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