TY - JOUR
T1 - Familial mesothelioma
T2 - Review and family study
AU - Lynch, Henry T.
AU - Katz, David
AU - Markvicka, Susan E.
PY - 1985/2/1
Y1 - 1985/2/1
N2 - To date, with few exceptions, primary attention to the etiology of malignant mesothelioma has been focused on environmental factors. However, several reports of familial aggregations of mesothelioma strongly support the supposition that host factors, in concert with environmental exposure, particularly asbestos, may contribute etiologically to an as yet unknown fraction of occurrences of this disease. However, in evaluation of familial mesothelioma, it is important to consider the possibility of household exposure to asbestos. We report a family in which two brothers with prolonged occupational asbestos exposure manifested malignant pleural mesotheliomas of similar histology.
AB - To date, with few exceptions, primary attention to the etiology of malignant mesothelioma has been focused on environmental factors. However, several reports of familial aggregations of mesothelioma strongly support the supposition that host factors, in concert with environmental exposure, particularly asbestos, may contribute etiologically to an as yet unknown fraction of occurrences of this disease. However, in evaluation of familial mesothelioma, it is important to consider the possibility of household exposure to asbestos. We report a family in which two brothers with prolonged occupational asbestos exposure manifested malignant pleural mesotheliomas of similar histology.
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U2 - 10.1016/0165-4608(85)90128-1
DO - 10.1016/0165-4608(85)90128-1
M3 - Article
C2 - 3967217
AN - SCOPUS:0021911785
VL - 15
SP - 25
EP - 35
JO - Cancer Genetics and Cytogenetics
JF - Cancer Genetics and Cytogenetics
SN - 0165-4608
IS - 1-2
ER -