Familial mesothelioma: Review and family study

Henry T. Lynch, David Katz, Susan E. Markvicka

Research output: Contribution to journalArticle

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Abstract

To date, with few exceptions, primary attention to the etiology of malignant mesothelioma has been focused on environmental factors. However, several reports of familial aggregations of mesothelioma strongly support the supposition that host factors, in concert with environmental exposure, particularly asbestos, may contribute etiologically to an as yet unknown fraction of occurrences of this disease. However, in evaluation of familial mesothelioma, it is important to consider the possibility of household exposure to asbestos. We report a family in which two brothers with prolonged occupational asbestos exposure manifested malignant pleural mesotheliomas of similar histology.

Original languageEnglish
Pages (from-to)25-35
Number of pages11
JournalCancer Genetics and Cytogenetics
Volume15
Issue number1-2
DOIs
StatePublished - Feb 1 1985

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All Science Journal Classification (ASJC) codes

  • Cancer Research
  • Genetics
  • Molecular Biology

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