Abstract
Familial ovarian carcinoma has been recognized with increased frequency during the past decade commensurate with physician attention to family history. Putative autosomal dominant inheritance of this heterogeneous problem mandates attention to both paternal and maternal lineages. A family with probable paternal transmission of breast/ovarian carcinoma is presented. One family member had findings consonant with papillary serous adenocarcinoma of ovarian origin, which may have arisen directly from extra-ovarian pelvic mesothelium. These and other clinical nuances of familial ovarian carcinoma are discussed in order to aid physicians in understanding the natural history, surveillance, and management of familial ovarian carcinoma.
| Original language | English |
|---|---|
| Pages (from-to) | 1073-1076 |
| Number of pages | 4 |
| Journal | American Journal of Medicine |
| Volume | 81 |
| Issue number | 6 |
| DOIs | |
| State | Published - 1986 |
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All Science Journal Classification (ASJC) codes
- Nursing(all)
Cite this
Familial ovarian carcinoma. Clinical nuances. / Lynch, Henry T.; Bewtra, Chhanda; Lynch, Jane F.
In: American Journal of Medicine, Vol. 81, No. 6, 1986, p. 1073-1076.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Familial ovarian carcinoma. Clinical nuances
AU - Lynch, Henry T.
AU - Bewtra, Chhanda
AU - Lynch, Jane F.
PY - 1986
Y1 - 1986
N2 - Familial ovarian carcinoma has been recognized with increased frequency during the past decade commensurate with physician attention to family history. Putative autosomal dominant inheritance of this heterogeneous problem mandates attention to both paternal and maternal lineages. A family with probable paternal transmission of breast/ovarian carcinoma is presented. One family member had findings consonant with papillary serous adenocarcinoma of ovarian origin, which may have arisen directly from extra-ovarian pelvic mesothelium. These and other clinical nuances of familial ovarian carcinoma are discussed in order to aid physicians in understanding the natural history, surveillance, and management of familial ovarian carcinoma.
AB - Familial ovarian carcinoma has been recognized with increased frequency during the past decade commensurate with physician attention to family history. Putative autosomal dominant inheritance of this heterogeneous problem mandates attention to both paternal and maternal lineages. A family with probable paternal transmission of breast/ovarian carcinoma is presented. One family member had findings consonant with papillary serous adenocarcinoma of ovarian origin, which may have arisen directly from extra-ovarian pelvic mesothelium. These and other clinical nuances of familial ovarian carcinoma are discussed in order to aid physicians in understanding the natural history, surveillance, and management of familial ovarian carcinoma.
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U2 - 10.1016/0002-9343(86)90411-0
DO - 10.1016/0002-9343(86)90411-0
M3 - Article
C2 - 3799638
AN - SCOPUS:0022965596
VL - 81
SP - 1073
EP - 1076
JO - American Journal of Medicine
JF - American Journal of Medicine
SN - 0002-9343
IS - 6
ER -