Fluoride therapy for the vertebral crush fracture syndrome. A status report

R. P. Heaney, D. J. Baylink, C. C. Johnston, L. J. Melton, P. J. Meunier, T. M. Murray, C. Nagant de Deuxchaisnes

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

Fluoride has been proposed as a therapy for the vertebral crush fracture syndrome for many years; such proposals have been based largely on the well-characterized syndrome of fluoride intoxication (fluorosis), which is marked by increased skeletal mass and sometimes exuberant bony overgrowths. For various reasons, including the inability to develop a patentable product, the clinical studies necessary to follow this lead and establish efficacy and safety have proceeded slowly. This report represents points of concurrent regarding the efficacy and safety of fluoride therapy and considerations relevant to patient management that were developed among conferees at the International Workshop on Fluoride and Bone.

Original languageEnglish
Pages (from-to)678-680
Number of pages3
JournalAnnals of Internal Medicine
Volume111
Issue number8
StatePublished - 1989

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Crush Syndrome
Fluorides
Safety
Therapeutics
Education
Bone and Bones
Crush Injuries

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Heaney, R. P., Baylink, D. J., Johnston, C. C., Melton, L. J., Meunier, P. J., Murray, T. M., & Nagant de Deuxchaisnes, C. (1989). Fluoride therapy for the vertebral crush fracture syndrome. A status report. Annals of Internal Medicine, 111(8), 678-680.

Fluoride therapy for the vertebral crush fracture syndrome. A status report. / Heaney, R. P.; Baylink, D. J.; Johnston, C. C.; Melton, L. J.; Meunier, P. J.; Murray, T. M.; Nagant de Deuxchaisnes, C.

In: Annals of Internal Medicine, Vol. 111, No. 8, 1989, p. 678-680.

Research output: Contribution to journalArticle

Heaney, RP, Baylink, DJ, Johnston, CC, Melton, LJ, Meunier, PJ, Murray, TM & Nagant de Deuxchaisnes, C 1989, 'Fluoride therapy for the vertebral crush fracture syndrome. A status report', Annals of Internal Medicine, vol. 111, no. 8, pp. 678-680.
Heaney RP, Baylink DJ, Johnston CC, Melton LJ, Meunier PJ, Murray TM et al. Fluoride therapy for the vertebral crush fracture syndrome. A status report. Annals of Internal Medicine. 1989;111(8):678-680.
Heaney, R. P. ; Baylink, D. J. ; Johnston, C. C. ; Melton, L. J. ; Meunier, P. J. ; Murray, T. M. ; Nagant de Deuxchaisnes, C. / Fluoride therapy for the vertebral crush fracture syndrome. A status report. In: Annals of Internal Medicine. 1989 ; Vol. 111, No. 8. pp. 678-680.
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