FREQUENCY OF OSTEOMALACIA AND OSTEOPOROSIS IN FRACTURES OF THE PROXIMAL FEMUR

J. E. Aaron, L. Stasiak, John Christopher G. Gallagher, E. B. Longton, M. Nicholson, J. Anderson, B. E C Nordin

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Abstract

A quantitative histological examination was made of iliac-crest biopsy specimens obtained from 125 cases of fracture of the proximal femur (102 women and 23 men). 35 women (34%) demonstrated a more severe degree of osteoporosis than would be expected for their age and 35 (including 10 of those with osteoporosis) had some evidence of osteomalacia. There was some evidence of osteomalacia in 11 (47%) men. 5 women and 2 men with osteomalacia had previously undergone partial gastrectomy. It is suggested that osteomalacia in the elderly makes an important contribution to the steep rise in femoral-neck fractures with advancing age in the U.K. and that this is attributable to an absolute or relative deficiency of vitamin D. It is also suggested that at least some of the osteoporotic component may also be attributable to a degree of vitamin-D deficiency sufficient to cause malabsorption of calcium but not sufficient to produce osteomalacia.

Original languageEnglish
Pages (from-to)229-233
Number of pages5
JournalThe Lancet
Volume303
Issue number7851
DOIs
StatePublished - Feb 16 1974
Externally publishedYes

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Osteomalacia
Femur
Osteoporosis
Vitamin D Deficiency
Femoral Neck Fractures
Gastrectomy
Calcium
Biopsy

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Aaron, J. E., Stasiak, L., Gallagher, J. C. G., Longton, E. B., Nicholson, M., Anderson, J., & Nordin, B. E. C. (1974). FREQUENCY OF OSTEOMALACIA AND OSTEOPOROSIS IN FRACTURES OF THE PROXIMAL FEMUR. The Lancet, 303(7851), 229-233. https://doi.org/10.1016/S0140-6736(74)92545-8

FREQUENCY OF OSTEOMALACIA AND OSTEOPOROSIS IN FRACTURES OF THE PROXIMAL FEMUR. / Aaron, J. E.; Stasiak, L.; Gallagher, John Christopher G.; Longton, E. B.; Nicholson, M.; Anderson, J.; Nordin, B. E C.

In: The Lancet, Vol. 303, No. 7851, 16.02.1974, p. 229-233.

Research output: Contribution to journalArticle

Aaron, JE, Stasiak, L, Gallagher, JCG, Longton, EB, Nicholson, M, Anderson, J & Nordin, BEC 1974, 'FREQUENCY OF OSTEOMALACIA AND OSTEOPOROSIS IN FRACTURES OF THE PROXIMAL FEMUR', The Lancet, vol. 303, no. 7851, pp. 229-233. https://doi.org/10.1016/S0140-6736(74)92545-8
Aaron JE, Stasiak L, Gallagher JCG, Longton EB, Nicholson M, Anderson J et al. FREQUENCY OF OSTEOMALACIA AND OSTEOPOROSIS IN FRACTURES OF THE PROXIMAL FEMUR. The Lancet. 1974 Feb 16;303(7851):229-233. https://doi.org/10.1016/S0140-6736(74)92545-8
Aaron, J. E. ; Stasiak, L. ; Gallagher, John Christopher G. ; Longton, E. B. ; Nicholson, M. ; Anderson, J. ; Nordin, B. E C. / FREQUENCY OF OSTEOMALACIA AND OSTEOPOROSIS IN FRACTURES OF THE PROXIMAL FEMUR. In: The Lancet. 1974 ; Vol. 303, No. 7851. pp. 229-233.
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